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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (688) clinical trials

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

Headaches following combat-related post-concussive injury are common, and in some patients can increase in frequency and severity to become very debilitating. Posttraumatic headaches (PTHAs), particularly those following blast-related head injury, can be resistant to standard headache therapies. The objective of this study is to evaluate the effectiveness of the medication ...

Phase

Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study

This study is a Phase III, randomized, double blind, multi-center, active controlled, 2-treatment arm, parallel group, non-inferiority study to evaluate the efficacy and safety of diclofenac diethylamine 2.32% gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily for 7 days in participants with acute ankle sprain. ...

Phase

Addiction Treatment in Primary Care Expansion

Among Veterans receiving healthcare from the Veterans Health Administration (VA), there has been sharp rise in the number of veterans diagnosed with opioid use disorder (OUD). In 2013, 25,031 Veterans had OUD and in 2017, Veterans with OUD nearly tripled to 69,142.6 As the largest direct provider of addiction treatment ...

Phase N/A

Electromyographic Study for the Help and Guidance of BoNTA Administration in the Treatment of Chronic Pelvic Floor Pain

Chronic pelvic pain (CPP) is a common presenting complaint affecting approximately 15-40 % of women aged 18-50 in western countries and 5-43% of women in most developing countries. It is debilitating and has a large socio- economic impact, with a 45%reduction in work productivity, and a 15% increase in absence ...

Phase

A Phase 1 Study to Evaluate Pregabalin and Acetaminophen in Healthy Volunteers

This is a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to determine a maximum tolerated dose (MTD) of IV PGB and to evaluate the safety, tolerability, and PK of an admixture of IV PGB and a fixed dose of 1300 mg IV APAP in healthy adult ...

Phase

CandeSpartan Study. Candesartan Spanish Response-prediction and Tolerability Study

CandeSpartan Study Candesartan Spanish Response-prediction and Tolerability study Observational study on response predictors and tolerability of Candesartan in usual clinical practice INTRODUCTION Migraine is a neurological disease with a prevalence of 14% of the population 1, 2. It is the second most disabling disease in terms of years of life ...

Phase N/A

Monitoring Postoperative Patient-controlled Analgesia (PCA)

Investigators will conduct a prospective intervention study including both nurses and patients in the study group. A web-based questionnaire will be used to collect the data from the participators. Inclusion criteria for the study group consisting of nurses will be registered nurses working in one of the two surgical wards ...

Phase N/A

Pilot Syndros Decreasing Use of Opioids in Breast Cancer Subjects With Bone Mets

This a prospective single arm study enrolling patients with bone metastases from breast cancer who have been on opioid therapy for bone pain for at least 4 weeks. All patients start on Syndros at 4.2 mg po BID for 3 days, if tolerated without side effects the dose is increased ...

Phase N/A

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

Chronic musculoskeletal pain (CMP) is the most common, non-malignant disabling condition that affects at least one in four older people. The most common painful musculoskeletal conditions among older adults are osteoarthritis, low back pain, fibromyalgia, chronic shoulder pain, knee pain, myofascial pain syndrome and previous fracture sites. Recent studies demonstrate ...

Phase N/A

Efficacy and Safety of Erenumab in Pediatric Subjects With Episodic Migraine

This study is a Phase 3, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with episodic migraine. The trial consists of four phases: screening (up to 3 weeks of initial ...

Phase