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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (245) clinical trials

"Follow the Sutures". A New Procedure for Injection of Botulinum Toxin for Chronic Migraine

There is no doubt that chronic migraine is a large public health problem, which is both disabling and costly. Many patients and headache doctors see Botulinum toxin (Botox) treatment as a big stride forward, but it is a problem that the effect has been shown in only one study, with ...


Managing MTBI-related Headaches With rTMS

Headache is one of the most common debilitating chronic pain conditions in either active or retired military personnel with MTBI. This high prevalence of persistent chronic headache is often associated with neuropsychological dysfunction in mood, attention, and memory, which casts a profound negative impact on patients' quality of life and ...

Phase N/A

Study of Efficacy and Safety of AMG 334 in Adult Episodic Migraine Patients

The purpose of this study is to evaluate the efficacy and safety of AMG334 in countries beyond the United States (US) and European Union (EU).


Migraine Relief After Patent Foramen Ovale Closure: a Single Center Analysis

The Study will evaluate the results of approximately 100 subjects from a single center study registered in this trial. Subjects who experienced transient ischemic attack (TIA) or stroke with a clinical indication to PFO closure and symptomatic for migraine with/o aura are considered for a migraine score analysis at baseline ...

Phase N/A

Testing myWHI: Online Self-help Programs for Headaches

This randomized controlled trial will compare the effectiveness of two online self-guided programs for youth and young adults with migraine against usual care.

Phase N/A

Introvision for Migraine and Headaches

Randomized, single-center, waiting-list control group study: Introvision as preventative in Migraine Randomized, single center, waiting-list group control study to evaluate the effect of Introvison, a mental and emotional self regulation method to reduce headache days in patients with migraine, migraine and tension type headache and chronic migraine. The number of ...

Phase N/A

The Effect of Ganglion Sphenopalatine Block (GSP-block) Versus Placebo on Postdural Puncture Headache

Adult patients with postdural puncture headache will be enrolled in the study. The patients will be randomised to receive a ganglion sphenopalatine block (GSP-block) with either local anesthetic (lidocaine + ropivacaine) or placebo (isotone NaCl). Primary outcome is hyperactivity in the sphenopalatine ganglion assessed by pain intensity (0-100mm on a ...


A Study of the Effect of a Disease-Specific Migraine Smart Phone Application (App) on Participant Care

The purpose of this study is to determine whether using a smart phone application to foster communication between study participants and their doctor will impact care. Participants must have a history of migraine or have recently been prescribed a common medicine to treat migraine. The study will last about one ...

Phase N/A

CHOCOlate MeLatonin for AdolescenT MigrainE

This pilot randomized trial is a dose-finding study to determine which dose of melatonin is most effective for treating acute migraine in children and adolescents who have episodic migraine. We will identify the most effective dose to pull forward into a future fully-powered placebo-controlled efficacy study. If both doses are ...


Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage

Persistent headache is a significant medical issue that affects 20% of patients who survive an aneurysmal subarachnoid hemorrhage (SAH). This headache may last years, severely affecting quality of life. Laboratory evidence suggests that the persistent headache may be a result of a maladaptive neuroinflammatory response to the hemorrhage injury that ...

Phase N/A