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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (213) clinical trials

Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo

Vertigo is among the most common symptoms associated with migraine and affects 26.5% of migraine sufferers. Migraine Associated Vertigo (MAV) has a dramatic impact on daily life, impacting work, relationships, and even activities of daily living. At the current time, the mainstay of therapy for migraine is pharmaceutical intervention, either ...

Phase N/A

Neurology Inpatient Clinical Education Trial

The objective of this study is to compare the effectiveness of a personalized patient education program to the current hospital education and evaluate its impact using patient satisfaction scores. The investigators hypothesize that a personalized patient education intervention will increase patient's understanding of their diagnosis and satisfaction with the care ...

Phase N/A

Transcranial Magnetic Stimulation in Episodic Migraine (Magnet-EM)

Migraine patients according to International Headache Society criteria will be allocated randomly into two treatment arms. 1 group will receive Active r-TMS and 1 group will receive sham r-TMS for treatment phase (5 sessions). Assessment will be made at baseline (month 1), month 2 (1 month after first treatment session), ...

Phase N/A

Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache

The primary objectives of the study are to study the effectiveness of SP ganglion block in relieving post-dural puncture headache in terms of : Number of subjects who get relief of pain The onset time to pain relief after application of block The duration of pain relief The incidence of ...


Predicting Migraine Attacks Based on Environmental and Behavioral Changes as Detected From the Smartphone

Migraine attacks can damage quality of life and lead to missed work days if not treated in time. These attacks last for about 4-72 hours, accompanied by headache and other symptoms. The time window for early intervention, which can potentially reduce the severity of an attack, lasts 2-48 hours before ...

Phase N/A

Study of Pediatric Migraine: The Pediatric Migraine Registry

This is a multi-center registry that will prospectively collect regulatory compliant data from children and adolescents with migraine. This study will enroll approximately 200 participants from approximately 20 sites and will examine migraine symptoms, therapeutics used, and biomarkers associated with migraine.

Phase N/A

Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines

The study is a prospective randomized, multi-center, double-blind, parallel, sham-controlled study, designed for comparison of two parallel groups, gammaCore-Sapphire (active treatment) and a sham (inactive) treatment. The study period will begin with a four-week run-in period, during which there is no investigational treatment. The purpose of the run-in period will ...

Phase N/A

The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Patients With Migraine

This is a prospective multicenter study of Chinese population. Participants (normal individuals without migraine and migraineurs) are included after standardized diagnostic procedures (TCD and migraine diagnosis). For all the participants, brain MRI and c-TCD are required. Up to 10-15 study sites nationwide will be needed to recruit the planned participant ...

Phase N/A

Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache

The reasons and justification of choosing an open-label design are the following: To date, there are no evidence for prophylactic drugs treating post-traumatic headache. Post-traumatic headache patients are notoriously known to be refractory to prophylactic treatment and have usually tried several prophylactic drugs such as amitriptylin, which is recommended as ...


Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department

Investigators will conduct a randomized trial to evaluate the impact of a comprehensive migraine treatment program on the quality of life for migraineurs with frequent and disabling headaches who present to the ED. The intervention (PM+PMR) will combine acute treatment, migraine preventive medication-topiramate, and the APP with PMR. Data from ...