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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (11) clinical trials

Prophylactic Effects of Psilocybin on Chronic Cluster Headache

Cluster headache (CH) is one of the most painful conditions known. CH affects 1 out 1000 and exists in two well-defined forms: episodic (ECH) and chronic (CCH). Ten to fifteen percent of patients have CCH and have less than three months of pain-free time during a year. Medical treatment for …

Phase

Oral NSAI Versus Paracetamol or Placebo as a Second Line Treatment for Renal Colics

Renal colic (RC)are a frequent cause of consultation in the emergency departement (ED). They count for approximatively 20% of patients presenting to the ED with severe acute onset abdominal pain. The first line treatment of renal colics is based on NSAI drugs associated with antalgics and is further investigated in …

Phase

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

Headaches following combat-related post-concussive injury are common, and in some patients can increase in frequency and severity to become very debilitating. Posttraumatic headaches (PTHAs), particularly those following blast-related head injury, can be resistant to standard headache therapies. The objective of this study is to evaluate the effectiveness of the medication …

Phase

Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children

The purpose of this study is to investigate low-dose naltrexone for the treatment of new daily persistent headache (NDPH) in adolescents ages 10-17. New daily persistent headache (NDPH) is a primary headache disorder characterized by continuous pain experienced for at least 3 months from distinct onset. Patients with NDPH have …

Phase

Intravenous Gammaglobulin for Sickle Cell Pain Crises

Patients will be randomized to a single dose of IVIG versus normal saline placebo during an uncomplicated pain crisis. Length of VOC and other secondary endpoints will be monitored.

Phase

Application Software in Dosage Adjustment for Advanced Cancer Patients With Pain

The purpose of this trial is to determine whether Application (APP) would help clinical doctors to adjust the dose of Oxycodone Hydrochloride Prolonged-release Tablets in advanced patients with cancer pain.

Phase

Status Migrainosus - Differentiating Between Responders and Non-responders

Recently, there has been a major focus on "evidence-based" treatments. Who could possibly argue against basing decisions on data? Since the highest level of evidence is derived from randomized double-blind controlled therapeutic trials that consider treatments rendered to large groups of patients with general diagnoses (e.g., migraine) or from a …

Phase

Treatment of Chronic Migraine Headaches.

A combination of dexamethasone, lidocaine and thiamine (pat.), may bring changes in the pattern of sympathetic and parasympathetic nerve signaling at the level vasa nervorum. These changes may down-regulate the hyperexcitable sympathetic signals at the level of adventitia and consequently the medial layer of vasa nervorum and providing long term …

Phase

Transcranial Direct Current Simulation in Chronic Migraine

The patients will be randomized into 1 of 3 groups: active tDCS over primary motor cortex, active tDCS over prefrontal cortex, sham tDCS. Each group will receive treatment for 20 minutes a day, 3 days a week for 4 weeks.

Phase

APIC-CF Therapy for Mild to Moderate Osteoarthritis of the Knee

The mechanism of Osteoarthritis (OA) is complex, however the investigators know that cartilage breakdown follows changes in certain cells in the cartilage called chondrocytes, leading to proteases that break down cartilage. There is a protein in the human blood called alpha-2-macroglobulin that can trap these proteases and prevent the breakdown …

Phase