Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 187 clinical trials
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

This phase I trial studies the side effects and best dose of CD4+ and CD8+ HA-1 T cell receptor (TCR) (HA-1 T TCR) T cells in treating patients with acute leukemia that persists, has come back

tyrosine
blast cells
chronic myeloid leukemia
flow cytometry
myelomonocytic leukemia
  • 73 views
  • 07 Oct, 2022
  • 1 location
Structural and Functional Cerebral Changes After Infusion of ATP Sensitive Potassium Channel Opener Levcromakalim.

The aim of the present study to investigate whether Opening of KATP channels causes migraine pain by activation of meningeal nociceptors and ascending trigeminal nociceptive pathways. Opening of KATP channels causes migraine aura by induction of CSD.

levcromakalim
potassium
sumatriptan
migraine
  • 0 views
  • 22 Oct, 2022
  • 1 location
The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers

To investigate the effect of levcromakalim/placebo infusion on cranial arteries after glibenclamide administration.

levcromakalim
glibenclamide
Accepts healthy volunteers
  • 12 views
  • 04 Oct, 2022
  • 3 locations
Treatment of Acute Post-Traumatic Headache With Erenumab 140 mg, Military Service Members and Civilians With Mild TBI: A Randomized, Double Blind, Placebo Controlled, Multicenter 12-week Duration Study Followed by a 4-week Open-Label Safety Extension

This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild

  • 0 views
  • 28 Oct, 2022
  • 3 locations
Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA

, randomized, placebo-controlled, stepwise trial. Amobarbital will be delivered to ankle joints in solution with hyaluronic acid (HA) as a vehicle. Amobarbital/HA injections (active dose) will be compared to

hyaluronic acid
  • 0 views
  • 04 Oct, 2022
  • 1 location
Objectively Diagnose and Monitor Treatment of Light Sensitivity

The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses

headache
photophobia
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing

  • 8 views
  • 04 Oct, 2022
  • 1 location
A Phase 4, Open-Label Study to Evaluate the Safety and Tolerability of Daily Dosing of Rimegepant in Episodic Migraine Prevention

The purpose of this study is to further evaluate the long-term safety and tolerability of daily dosing of rimegepant for the prevention of episodic migraine.

headache
episodic migraine
  • 0 views
  • 22 Oct, 2022
  • 19 locations
Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine

chronic migraine headache. The Tx360® is a nasal applicator which is cleared through the FDA for transnasal medication delivery, including delivery to the SPG. The SPG has been implicated in a variety of

headache
chronic migraine
tension
daily headaches
  • 224 views
  • 07 Oct, 2022
  • 7 locations
Haemophilia and Bone Loss PHILEOS Study (PHILEOS)

Haemophilia is a rare bleeding disorder, characterized by factor VIII (HA) or factor IX (HB) deficiency. The absence or the reduction of fVIII or fIX result in impaired thrombin generation and

christmas disease
hemarthrosis
thrombin
deficiency
factor ix
  • 15 views
  • 24 Oct, 2022
  • 19 locations