Lupus Clinical Trials

A listing of Lupus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 254 clinical trials
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis (POSTERITY)

than 18 with biopsy-confirmed proliferative lupus nephritis (LN).

mycophenolate
diphenhydramine
nephritis
mammogram
proteinuria
  • 0 views
  • 10 Jul, 2022
  • 18 locations
Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis (SELUNE)

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

glomerular filtration rate
urinary sediment
nephritis
mammogram
  • 426 views
  • 24 Jul, 2022
  • 161 locations
A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis (REGENCY)

) class III or IV lupus nephritis (LN) when added on to standard-of-care therapy consisting of mycophenolate mofetil (MMF) and corticosteroids.

mycophenolate
diphenhydramine
nephritis
mammogram
prednisone
  • 8 views
  • 10 Jul, 2022
  • 100 locations
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis (SIRIUS-LN)

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult participants with active LN

systemic lupus erythematosus
rheumatism
induction therapy
nephritis
glomerulonephritis
  • 0 views
  • 10 Aug, 2022
  • 15 locations
COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

>Systemic Lupus Erythematosus (SLE) Rheumatoid Arthritis (RA) Multiple Sclerosis (MS) Systemic Sclerosis (SSc), and Pemphigus. This study will focus on 4

disease or disorder
ocrelizumab
arthritis
prednisone
dermatomyositis
  • 79 views
  • 24 Jul, 2022
  • 20 locations
Deployment o the Multidisciplinary Prospective Cohort Imminent (IMMINeNT)

Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite …

disease or disorder
  • 2 views
  • 09 Jun, 2022
  • 1 location
Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Primary Objective: Assess the efficacy of SAR443122 in cutaneous lupus erythematosus (CLE) Secondary Objectives: Assess the effect of SAR443122 on the

  • 19 views
  • 15 Aug, 2022
  • 49 locations
Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Primary Objective: Assess the efficacy of SAR443122 in cutaneous lupus erythematosus (CLE) Secondary Objectives: Assess the effect of SAR443122 on the

  • 3 views
  • 08 Aug, 2022
  • 49 locations
Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE (EMERALD)

systemic juvenile idiopathic arthritis and adult onset Still's disease) or with sHLH/MAS in systemic lupus erythematous, resenting an inadequate response to high dose glucocorticoid treatment.

lupus
arthritis
  • 0 views
  • 14 Jul, 2022
  • 21 locations
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart preservation (NIHP) in a randomized clinical multicentre trial. The primary hypothesis is that the non-ischemic hypothermic cardioplegic preservation (NIHP) is safe and superior to ischemic cold static storage (ICSS) …

heart transplant
heart disease
lupus
heart transplantation
coagulopathy
  • 0 views
  • 09 Mar, 2021
  • 9 locations