Lupus Clinical Trials

Patient self-management is a fundamental component in arthritis care that is often neglected. Physical activity is an essential part of self-management, however, less than half of people with arthritis are active. There are several factors that are associated with low physical activity participation such as motivation, doubts about the effectiveness ...

Rosacea is a common inflammatory skin disease affecting up to 10% of adults. Despite this, the etiology of rosacea is unclear, although there may be a genetic predisposition (Chang et al., 2015). Currently, there is no cure. Rosacea can lead to scarring, itching, burning, and is associated with anxiety and ...

Recruitment of patients with APS and SLE treated. Retrospective and prospective register.

Objectives To detect pulmonary hypertension amongst patients with connective tissue diseases through systematic screening To understand the prevalence of pulmonary hypertension in Chinese patients with connective tissue diseases Study design: The study is a territory-wide pulmonary hypertension screening project. Patients fulfilling the inclusion and exclusion criteria will undergo screen echocardiography ...

Atherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity and mortality, especially in patients with autoimmune disorders such as systemic lupus erythematosus (lupus) and rheumatoid arthritis (RA). We have found that immune and inflammatory mediators promote atherosclerosis by disabling mechanisms that prevent cells of the artery wall from being ...

This is a single site, single arm open label study of Azelaic Acid foam 15% for the treatment of moderate to severe papulopustular rosacea. All patients will apply Azelaic Acid foam twice daily. At scheduled visits, high resolution equipment will be used to measure 3D topographical values for elevation of ...

Patients will be divided into two groups, arm A and arm B according to two different methods adopted in their first needle, which refers to the modified wet suction technique or 5ml dry suction technique.Take the solid occupying lesion diagnosis accuracy as the research major indicator to compare the the ...

This study investigate mycophenic acid (MPA) pharmacokinetics and pharmacogenomics and their impact on the clinical outcomes in lupus nephritis (LN) patients. Lupus nephritis patients (both active or inactive) will be recruited. MPA levels will be checked at 1, 2, 4, 8, 10, 12 hrs after MMF administration by an enzymatic ...

Proliferative glomerulonephritis is a common and severe manifestation of systemic lupus erythematosus (SLE) that usually requires intensive therapy with high doses of glucocorticosteroids and cytotoxic drugs, such as intravenous (IV) cyclophosphamide (CYC). The objective of this Trial is to compare leflunomide (LEF) and azathioprine (AZA), in terms of efficacy and ...

Primary Objective: To assess adherence to topical brimonidine for the treatment of rosacea. Secondary Objectives: To determine the impact of reported adherence on rosacea outcomes, To identify factors that affect adherence to rosacea treatment and to assess QOL. Study Design An investigator-blinded, prospective, 6 month study of subjects with persistent ...