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Lupus Clinical Trials

A listing of Lupus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (325) clinical trials

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus

The reason for this study is to see how effective and safe the study drug known as baricitinib is in participants with systemic lupus erythematosus (SLE).


Study of Oral SKI-O-703 SYK Inhibitor in Patients With Persistent and Chronic Immune Thrombocytopenia (ITP)

This study will evaluate the efficacy, safety, tolerability,pharmacokinetics (PK), and pharmacodynamics (PD) of select (200 mg BID and 400 mg BID) doses of SKI-O-703 in persistent and chronic ITP patients who have failed to respond or relapsed after prior therapy, with a platelet count <30,000/L. on 2 occasions at least ...


An Exploratory Maintenance Trial of BI 655064 in Patients With Lupus Nephritis

Initially planned participating countries: Argentina, Australia, Canada, Colombia, Czech Republic, France, Germany, Greece, Hong Kong, Italy, Japan, Republic of Korea, Malaysia, Mexico, Philippines, Poland, Portugal, Serbia, Spain, Taiwan, Thailand, United Kingdom, United States


Study to Assess the Metabolic Impact of IRTA and Patients Satisfaction in Type 1 Diabetic Patients Treated by Either Insulin Pump or Multiple Daily Insulin Injections and Using Freestyle Libre a Real-time Continuous Glucose Monitoring

Freestyle Libre continuous glucose monitoring (CGM) system may improve glycemic control. However, this system contributes to the complexity of insulin adjustment by the diversity of the data delivered by CGM system. Insulin Real-Time Advisor (IRTA), a decision support software, has been developed in order to guide patients in the adaptation ...

Phase N/A

Effects of Temperature Control Liner Materials on Long-Term Outcomes of Prothesis Use

Background: The proposed work will generate evidence-based practice guidance for temperature control liner technologies and allow providers to optimize care to Service members and Veterans with limb loss. Sizeable numbers of Service members and Veterans live with limb loss, mostly due to traumatic musculoskeletal injury. Addressing the resulting functional deficit ...

Phase N/A

Insulin Pump to Multiple Daily Injection Transition Clinical Trial

Second generation long acting insulin, insulin degludec, has been shown to improve glycemic control and reduce hypoglycemia in patients with type 1 diabetes and insulin treated type 2 diabetes. However, it takes about 48 hours before glycemic benefits are noticeable. Therefore, transition from insulin pump to multiple daily injection using ...


Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

This is a pilot intervention study to evaluate preliminary evidence of the safety and effectiveness of a novel combination immunosuppressive regimen, Rituximab plus cyclosporine, in the treatment of idiopathic membranous nephropathy. Membranous nephropathy is a condition that affects the kidney and involves damage to the walls of tiny blood vessels ...


Peer Approaches to Lupus Self-management

The Peer Approaches to Lupus Self-Management (PALS) study is a randomized controlled trial designed to examine whether a new, culturally tailored peer mentoring intervention improves disease self-management, indicators of disease activity, and health related quality of life (HRQOL) in African American women with systemic lupus erythematosus (SLE). African American women ...

Phase N/A

Abatacept in Juvenile Dermatomyositis

JDM is a chronic systemic autoimmune disease with a predominance of muscle and skin inflammation of unknown etiology and varying prognosis. Children with JDM unresponsive to corticosteroids or other immunosuppressive medications face poor clinical and functional outcome and suffer various sequelae of the disease. Abatacept is a fully human soluble ...


Reducing Disparities in Medication Adherence in SLE

This is a pilot study to assess the feasibility of using Surescript refill data during the clinical encounter to improve medication adherence in patients with systemic lupus erythematosus

Phase N/A