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Cardiomyopathy Clinical Trials

A listing of Cardiomyopathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (226) clinical trials

Screening for Hereditary Transthyretin Related Amyloidosis - an Internationales Multicentre Epidemiological Protocol (TRAM)

Hereditary TransThyRetin Amyloidosis (hATTR) is a slowly progressive condition, that is transmitted as an autosomal dominant trait and is characterized by abnormal extracellular deposits of fibrillar, misfolded proteins (amyloid fibrils) in the body. Amyloid fibrils can be deposited in different body compartments, such as the nerves, heart, gastrointestinal tract, kidneys ...

Phase N/A

Limb-Girdle Muscular Dystrophy Type 2I in Norway

A single-center study with Norwegian nationwide enrollment. Data is based on questionnaires, patient journals, clinical examination, a set of functional tests and biomarkers, and patient reported outcomes. Clinical/ paraclinical tests are repeated after 2-years in order to measure disease progression. Both skeletal muscle, heart and respiratory function will be examined. ...

Phase N/A

Microvascular Endothelial Function in a Cohort of Patients With the Cardiac Form of Chronic Chagas Disease.

Chagas disease is an endemic anthropozoonosis in South America, caused by the protozoaTrypamosoma cruzi. Between 15 and 17 million people are estimated to be infected by the parasite in South America. During the chronic phase, 30 to 40% of patients develop the cardiac or intestinal forms of the disease. The ...

Phase N/A

Natural History of Duchenne Muscular Dystrophy

Study duration from FPFV: Q1 2019 to LPLV: Q3 2021 Primary Ojectives: To assess the natural disease course using standardized and disease appropriate evaluations over a period of 6 to 24 months in a cohort of young male subjects aged from 4 to 6 years at inclusion and diagnosed for ...

Phase N/A

Patient-centered and Clinical Outcomes After Minimally Invasive Cardiothoracic Surgery

Introduction Coronary artery disease is a leading cause of adult mortality worldwide. One of the most commonly performed surgical interventions to treat this vascular disease is a myocardial revascularization, mostly performed via a Coronary Artery Bypass Graft (CABG) (1). Over time, new developments in cardiac surgery have led to the ...

Phase N/A

Echocardiography Findings and Perioperative Outcomes in Children

This study evaluates the association between perioperative echocardiographic Doppler findings and clinical outcomes in pediatric patients undergoing cardiac surgery. In our center, anesthesiologists perform transthoracic or transesophageal echocardiography during perioperative period routinely in children undergoing surgery for congenital cardiac disease. Echocardiographic findings include the doppler patterns of hepatic vein, portal ...

Phase N/A

A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy

Adult patients with hypertrophic cardiomyopathy and without known atrial fibrillation or pacemaker/implantable cardiac defibrillation will undergo implantable loop recorder implantation. No direct interventions will be performed. Prospective observation of atrial and ventricular arrhythmia incidence and burden will be assessed, with additional analyses performed based on the presence or absence of ...

Phase N/A

Improving Detection of Dysphagia in the CICU

Cardiovascular diseases account for one third of all deaths in the world and will be responsible for an estimated 25 million deaths in 2020 alone.1 Heart surgery is therefore one of the most common therapeutic procedures performed to correct, reconstruct, or replace this life-sustaining organ. An increasingly reported consequence from ...

Phase N/A

Wearable Technology to Assess Gait Function in SMA and DMD

Spinal muscular atrophy (SMA) and Duchenne muscular dystrophy (DMD) are genetic disorders that often result in progressive weakness and impaired function. Results from this study will help characterize how gait is affected in SMA and DMD. This novel device can serve as a more affordable and versatile measurement instrument for ...

Phase N/A

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

The overall objective of this proposal is to validate the potential of noninvasive magnetic resonance imaging (MRI) and spectroscopy (MRS) to monitor disease progression and to serve as an outcome measure for clinical trials in Duchenne muscular dystrophy (DMD). DMD is one of the most devastating genetically linked neuromuscular diseases ...

Phase N/A