Search Medical Condition
Please enter condition
Please choose location
Clear Trial Filters

Cardiomyopathy Clinical Trials

A listing of Cardiomyopathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (12) clinical trials

Patients are needed to participate in a clinical research study evaluating SRP-4045, SRP-4053, Placebo for the treatment of DUCHENNE MUSCULAR DYSTROPHY, Muscular Dystrophy

This is a double-blind, placebo-controlled, multi-center study to evaluate the efficacy and safety of SRP-4045 and SRP-4053. Eligible patients with out-of-frame deletion mutations amenable to exon 45 or 53 skipping will be randomized to receive once weekly intravenous (IV) infusions of 30 mg/kg SRP-4045 or 30 mg/kg SRP-4053 respectively (combined-active ...


A clinical trial to evaluate treatments for patients with DUCHENNE MUSCULAR DYSTROPHY

Each subject will receive pamrevlumab (35 mg/kg) every two weeks by intravenous infusion for up to 156 weeks. After at least 10 to 12 subjects complete one year of treatment interim analysis may increase total subjects enrolled to approximately 32. All subjects will be closely monitored for safety. Efficacy assessments ...


A clinical trial sponsored by Pfizer for a research study for the treatment of DUCHENNE MUSCULAR DYSTROPHY

This study is an open-label extension to protocol B5161002 and will provide an assessment of the long term safety, efficacy, pharmacodynamics and pharmacokinetics of intravenous dosing of PF 06252616 in boys with Duchenne muscular dystrophy. Approximately 105 eligible subjects will be assigned to receive a monthly individualized maximum tolerated dose ...


A clinical trial seeking patients for a research study for the treatment of Transthyretin (TTR) Amyloid Cardiomyopathy

Global, Phase 3, double-blind, randomized, long-term extension study to evaluate the safety of oral daily dosing of 20 mg or 80 mg tafamidis meglumine in subjects with transthyretin cardiomyopathy (TTR-CM), who have completed 30 months of study treatment on Pfizer protocol B3461028, for up to 60 months or until local ...


A Phase 3 clinical study for patients using givinostat, placebo

Givinostat or placebo oral suspension (10 mg/mL) will be administered orally as 2 oral doses daily while the subject is in fed state, according to the child's weight. Study drug should be permanently stopped if any of the following occur: severe drug-related diarrhoea; any drug-related Serious Adverse Event; QTcF >500 ...


A clinical trial seeking patients for a research study for the treatment of Hypertrophic Cardiomyopathy

Participants will be healthy volunteers or subjects with the diagnosis of hypertrophic cardiomyopathy (HCM). All patients will a undergo a one time; medical history, physical examination, questionnaires, sleep observation in hospital, blood and urine samples, ultrasound scan of the heart, paced breathing test, ultrasound of brachial artery in the arm, ...

Phase N/A

Patients are needed to participate in a clinical research study for the treatment of Ventricular Fibrillation, Dilated cardiomyopathy, Ventricular tachycardia

Rationale: Sudden cardiac death, mainly caused by ventricular arrhythmias (VA), is a major cause of morbidity and mortality in non-ischemic cardiomyopathy (NICM). Therapies that effectively prevent VA are lacking. Improved understanding of the substrate and mechanisms of VA in NICM may allow more effective, individualized and substrate-based therapies to be ...

Phase N/A

A clinical research study for the treatment of DUCHENNE MUSCULAR DYSTROPHY

Magnetic Resonance Imaging (MRI) of the heart and breathing muscles, special breathing tests (called pulmonary function testing), special exercise tests (using a stationary bike), and possibly an echocardiogram (ultrasound of the heart, commonly known as an "echo") will be completed up to 4 times per year for up to 4 ...

Phase N/A

A clinical trial sponsored by University of Southern Denmark for a research study for the treatment of Dilated cardiomyopathy

Title Clinical and genetic examinations of dilated cardiomyopathy Background Dilated cardiomyopathy (DCM) is a severe disease of the heart muscle characterised by reduced pumping function and dilatation of the left ventricle without any obvious cause like hypertension, ischemic heart disease or heart valve disease. The patients often complain about shortness ...

Phase N/A

A clinical trial sponsored by Göteborg University for a research study for the treatment of Obstructive sleep apnea, Dilated cardiomyopathy

Sleep apnea, either obstructive (OSA) and central (CSA), occurs in more than half of all patients with heart failure (HF), and is associated with poor prognosis in these individuals. Dilated cardiomyopathy (DCM) is the most common type of cardiomyopathy and is defined as the presence of the left ventricle dilatation ...