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Cardiomyopathy Clinical Trials

A listing of Cardiomyopathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (234) clinical trials

This study is designed to assess the efficacy, safety and tolerability of ixmyelocel-T compared to placebo (vehicle control) when administered via transendocardial catheter-based injections to patients with end stage heart failure due to IDCM, who have no reasonable revascularization options (either surgical or percutaneous interventional) likely to provide clinical benefit. ...

Phase

In patients with symptomatic New York Heart Association (NYHA) Class II/III/IV dilated cardiomyopathy (DCM) in which mutations in the gene encoding the lamin A/C protein (LMNA) have been implicated: Primary Objective: NYHA Class II/III patients only: Evaluate the effect of ARRY-371797 on functional capacity (as measured by the 6-minute walk ...

Phase

Identification of NICM patients who are likely to develop ventricular tachyarrhythmias is challenging.   In the light of MADIT-RIT and ADVANCE III trials, modern programming of ICDs is targeting faster (188-200 bpm) and longer (>30 beats) episodes of ventricular tachyarrhythmias, that might serve as the endpoint related to a reduction ...

Phase N/A

Secondary Objectives All-cause mortality, VT or VF alone, risk of cardiac death, and sudden cardiac death for the total cohort, as well as by sex and by the implanted device type. Compare the predicted incidence of sudden death using the Seattle Proportional Risk score to the observed incidence in this ...

Phase N/A

Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury

This is an open-label, baseline-controlled study to be conducted. Adult male or nonpregnant female patients who have been referred for evaluation of dilated cardiomyopathy, ischemic cardiomyopathy, non-ischemic cardiomyopathy, atrial arrthymia and also patients who have received stem cell therapy related to both ischemic and dilated cardiomyopathy (under different trials) will ...

Phase

Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)

Participants will be healthy volunteers or subjects with the diagnosis of hypertrophic cardiomyopathy (HCM). All patients will a undergo a one time; medical history, physical examination, questionnaires, sleep observation in hospital, blood and urine samples, ultrasound scan of the heart, paced breathing test, ultrasound of brachial artery in the arm, ...

Phase N/A

DCM Precision Medicine Study

Dilated cardiomyopathy of unknown cause (DCM), known clinically as idiopathic dilated cardiomypathy, is the most common cardiomyopathy and is the leading cause of heart transplantation. DCM affects approximately one million individuals, and so has a major impact on US public health. DCM is commonly asymptomatic until very late in its ...

Phase N/A

Sleep Apnea and CRT Upgrading

Within the last decade cardiac resynchronization therapy (CRT) has been proven to be an effective therapy to reduce morbidity and mortality in chronic heart failure patients with wide QRS complex, in particular complete left bundle branch block. New indications have recently been established, including patients with mild symptoms and patients ...

Phase N/A

User-centred Assistive System for Arm Functions in Neuromuscular Subjects

Restore a lost function is a special experience for people affected by neuromuscular evolutive diseases. "From the patient's point of view improvement is measured by regaining lost abilities,-by being able to do something -anything-today I couldn't do yesterday ". Upper limb pain, stiffness and activity limitations have a crucial role ...

Phase N/A

Arrhythmogenic Substrate in Primary Cardiomyopathies

The present study is designed as a prospective single center study. All selected patients with implanted ICD to prevent VT/VF recurrence who are referred to the Arrhythmology Department of San Donato Milanese Hospital, for the management of a primary cardiomyopathy fulfilling the inclusion criteria will be enrolled. Primary cardiomyopathies include: ...

Phase N/A