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Testicular Cancer Clinical Trials

A listing of Testicular Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (38) clinical trials

Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors

Identification of late-effects through questionnaires and linkage to national registries. DNA samples will be gathered through buccal swabs or saliva kits and analysed with whole exome-sequencing.

Phase N/A

PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER

PRIMARY OBJECTIVES: I. To determine the response rates following treatment with PD 0332991 in the following malignancies: 1) Metastatic breast cancer, 2) Metastatic colorectal cancer, 3) Metastatic melanoma with CDK4 mutation or amplification, or 4) Cisplatin-refractory, unresectable germ cell tumors. II. To evaluate the safety and tolerability of PD 0332991 ...

Phase

Integrated Cancer Repository for Cancer Research

The integrated Cancer Repository for Cancer Research (iCaRe2 http://icare2project.org) is a unique sociotechnical resource for the collection and management of cancer and health-related data at the Fred & Pamela Buffett Cancer Center at University of Nebraska Medical Center (UNMC). The iCaRe2 is a multi-center, semantically-interoperable and easily-customizable cancer data resource ...

Phase N/A

Germ Cell Tumor and Testicular Tumor DNA Registry

This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, ...

Phase N/A

Vascular Fingerprint Validation Study

Since the introduction of cisplatin in the late seventies (1), the prognosis of metastatic testicular cancer patients has dramatically improved, with long-term survival rates of 80-90% (2). However, cure rates are compromised by the increased risk of cardiovascular events (3-5). Approximately 1-5% of the patients with metastatic testicular cancer develop ...

Phase N/A

Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment

Background Due to the remarkable improvement in treatments these last decades, long term survival can be expected in more than 80% of childhood cancer patients. Unfortunately, cancer treatments can be harmful to the gonads and can affect reproductive and endocrine functions. While loss of fertility is a major concern for ...

Phase N/A

Whole Body MRI With DWI for Monitoring Patients Treated for Testicular Cancer Stage II-III

AIMS AND HYPOTHESES The overall aim of this study is to reduce the risk of radiation-induced secondary cancers in patients operated for testicular cancer (TC) by replacing computed tomography (CT) as a follow-up imaging method with non-ionizing whole body magnetic resonance imaging (WB-MRI) including diffusion weighted imaging (DWI). Under the ...

Phase N/A

Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma

Therapy de-escalation in stage IIA/B seminoma represents an unmet need in clinical practice; efficacy of modern standard of care therapies for these patients is high and only a few patients show disease recurrence but short- and long-term toxicities are a major concern. The magnitude of long-term toxicities is often associated ...

Phase