Rheumatoid Arthritis (Pediatric) Clinical Trials

A listing of Rheumatoid Arthritis (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8 clinical trials
Safety of Splenic Stimulation for RA

This study will evaluate the safety and tolerability of stimulating the splenic neurovascular bundle (NVB) with the Galvani System, which consists of a lead, implantable pulse generator, external components and accessories. Participants eligible for implant will have active rheumatoid arthritis (RA) and have an inadequate response or intolerance to at …

antirheumatics
DMARD
  • 0 views
  • 01 Aug, 2021
  • 1 location
Lysophosphatidic Acid / Autotaxin Axis in Rheumatoid Lung Disease

Rheumatoid arthritis (RA) is a common chronic systemic autoimmune relapsing disease characterized by joint inflammation. Beside arthritis leading to progressive joint damage and loss of function, RA is also associated to extraarticular inflammatory conditions such as interstitial lung disease (ILD). This one develops in 30% of all RA patients with …

interstitial lung disease
  • 0 views
  • 01 Aug, 2021
  • 1 location
Safety and Efficacy Study of Human Umbilical Cord-Derived Mesenchymal Stem Cells(BC-U001) for Rheumatoid Arthritis

BC-U001 is an allogeneic fresh human umbilical cord-derived mesenchymal stem cell product, which showed therapeutic potential for rheumatoid arthritis(RA) based on its anti-inflammatory, immunomodulatory and tissue repair activities. The primary objective of this open-label, non-randomized, dose-escalation study is to evaluate the safety and tolerability of a single intravenous infusion of …

cyclic citrullinated peptide antibody
  • 0 views
  • 02 Aug, 2021
  • 1 location
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis

As stated by the European League Against Rheumatism (EULAR) and the Societe Francaise de Rhumatologie (SFR), treatment of patients with rheumatoid arthritis (RA) should target sustained remission or at least low disease activity. However, despite significant advances based on various combinations of conventional synthetic disease-modifying antirheumatic drugs (DMARDs) and biologic …

tumor necrosis factor
rheumatism
methotrexate
prednisone
rituximab
  • 0 views
  • 21 Jul, 2021
  • 20 locations
Do Nanobubbles Improve Joint Hypoxia?

Inflamed joints in patients with rheumatoid arthritis and psoriatic arthritis are characterized by low oxygen levels and inflammation. We propose to investigate whether tiny bubbles (nanobubbles) when given in a drink can alter oxygen level in joints. These nanobubbles are so small that they can enter the bloodstream when given …

rheumatism
hysterectomy
rheumatoid arthritis
oophorectomy
arthritis
  • 0 views
  • 21 Jul, 2021
  • 1 location
Vaccination Against SARS-Cov2 (COVID-19) in Chronic Inflammatory Rheumatism and Factors Determining Its Decision.

Rheumatoid arthritis and spondyloarthritis (ankylosing spondylitis and psoriatic arthritis mainly) are chronic inflammatory rheumatism (RIC), frequently onset in young adults. The prevalence is respectively 0.3 to 0.8% and 0.4%. or about 600,000 people. The "basic" treatments (DMARDs), essential to control the progression of the disease, are classified into csDMARDs (chemical), …

DMARD
rheumatism
methotrexate
psoriatic arthritis
ankylosing spondylitis
  • 0 views
  • 01 Aug, 2021
  • 1 location
The Role of Microbiome on Biological Therapy Efficacy in axSpA and RA

Spondyloarthritis (SpA) and Rheumatoid arthritis (RA) are among the most common chronic inflammatory rheumatic diseases. Introduction of Tumor Necrosis Factor alpha inhibitors (TNFi) to the therapeutic strategy improved acute inflammation and pain, but a significant percentage of patients develop severe adverse events or are still non responders or incomplete responders …

tumor necrosis factor
prednisolone
corticosteroids
antirheumatics
DMARD
  • 0 views
  • 30 Jul, 2021
  • 9 locations
Assessment of Interstitial Lung Disease in Rheumatoid Arthritis by Lung Ultrasound

The high resolution chest scan is the gold standard for the screening of interstitial lung disease, but this remains an onerous examination, and irradiating. Ultrasound could be used to detect these disorders with a very good sensitivity and specificity. This exam offers the advantage of being non radiating, inexpensive, and …

lung ultrasound
rheumatism
interstitial lung disease
  • 0 views
  • 01 Aug, 2021
  • 1 location