Neurofibromatosis Clinical Trials

A listing of Neurofibromatosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 57 clinical trials
Pegintron to Treat Plexiform Neurofibromas in Children and Young Adults

Background: Neurofibromatosis 1 (NF1) is a common autosomal dominant neurogenetic disorder characterized by diverse cutaneous, neurological, skeletal and neoplastic manifestations

  • 55 views
  • 07 Nov, 2020
  • 1 location
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 (DoDNAC)

Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1

Accepts healthy volunteers
  • 2 views
  • 11 Mar, 2022
  • 1 location
Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors (SEL-TH-1601)

In this research study the researchers want to learn more about the effects (both good and bad) the study drug selumetinib has on participants with neurofibromatosis type II (NF2) related tumor

monoclonal antibodies
multiple meningiomas
epilepsy
neurofibromatosis type 2
medical therapy
  • 639 views
  • 28 Apr, 2022
  • 1 location
Phase I/II Trial of PLX3397 in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)

. For Phase II, people ages 3 31 with a Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibroma (PN) that cannot be removed with surgery. Design

monoclonal antibodies
corticosteroids
malignant peripheral nerve sheath tumor
immunosuppressive agents
ejection fraction
  • 48 views
  • 23 Oct, 2022
  • 1 location
Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

This study has two primary objectives. The first is to determine if it is feasible and reliable for children and families with a diagnosis of Neurofibromatosis Type 1 (NF1) to use of blood

home blood pressure monitoring
  • 0 views
  • 07 Oct, 2022
  • 1 location
Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1 (OPTIMAL-SSI)

Children with neurofibromatosis are more likely to have difficulties related to their psychological and neurocognitive functioning (e.g., more likely to have depression, have social difficulties

  • 0 views
  • 29 May, 2022
  • 1 location
Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas (POPLAR-NF2)

This is a parallel-group, two-staged, Phase 2/3, randomized, multi-center study to investigate the efficacy and safety of REC-2282 in patients with progressive NF2 mutated meningiomas.

  • 0 views
  • 04 Oct, 2022
  • 5 locations
Resiliency Training in Adolescents With NF1 and NF2

This randomized controlled trial for resiliency training in adolescents with Neurofibromatosis 1 and Neurofibromatosis 2 via secure live video to determine the efficacy two stress and symptom

neurofibromatosis type 2
Accepts healthy volunteers
  • 2 views
  • 19 Feb, 2022
  • 1 location
A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis

AL2846 is a multi-target receptor tyrosine kinase inhibitor. The purpose of this study is to evaluate the safety and efficacy of AL2846 capsules in Chinese patients with type I neurofibromatosis

  • 0 views
  • 06 Oct, 2021
  • 1 location
  • 0 views
  • 04 Oct, 2022
  • 1 location