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Vaccines Clinical Trials

A listing of Vaccines medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (268) clinical trials

The purpose of this study is to compare the effects of an experimental drug to see if it is better at treating flu infections. This study will include approximately 7 visits to the research center. Qualified participants may receive study medications and all study related care including physical examinations and ...

Phase N/A

Developing and Assessing a Male Engagement Intervention in Option B+ in Malawi

In sub-Saharan Africa, engaging HIV-infected men in HIV care and treatment and engaging HIV-uninfected men in prevention has proven challenging. Along all steps of the HIV care-seeking cascade, men exhibit worse care-seeking behaviors. They are less likely to seek HIV testing and counseling (HTC), initiate combination antiretroviral therapy (cART), and ...

Phase N/A

Safety and Efficacy of Fixed Dose Combination Dolutegravir/Abacavir/Lamivudine FDC Initiated During Acute HIV Infection

The study will be conducted at the University of North Carolina in Chapel Hill, NC and Duke University in Durham, NC. All forty (40) participants will be enrolled for 96 weeks and will receive DTG/3TC/ABC FDC. We propose to evaluate the efficacy and time to viral suppression with DTG/3TC/ABC FDC ...

Phase N/A

The Association of Miltefosine and Pentoxifylline to Treat Mucosal Leishmaniasis: A Clinical Trial in Brazil

Mucocutaneous leishmaniasis is endemic in the central region of Brazil and other countries worldwide. The standard treatment with meglumine antimoniate has a high rate of important adverse effects. This interventional study consists in a randomized clinical trial to access efficacy and safety of the association of miltefosine and pentoxifylline compared ...

Phase

Immune Responses After a Four-site Intradermal Rabies Booster Vaccination in HIV-infected Adults

A four-site intradermal rabies booster vaccination has shown higher immune response than conventional intramuscular rabies booster vaccination in healthy persons. So, the investigators hypothesized the same outcome in HIV - infected patients.

Phase N/A

Optimizing Smoking Cessation for People With HIV/AIDS Who Smoke

We propose a factorial design strategy to evaluate the effects, individually and in combination, of the most promising pharmaco- and behavioral cessation therapies available for PLWH according to our review of the extant literature for HIV-infected and general population smokers. The sizable cohort and prospective design will also permit us ...

Phase

Web App Technology for Boys and Parents: Improving HPV Vaccine Uptake

The President's Cancer Advisory Board and the Centers for Disease Control have called for renewed efforts in promoting vaccination for Human Papillomavirus (HPV), including vaccination for adolescent boys, because the uptake of this new vaccine remains alarmingly low. Currently, less than 15% of adolescent boys have received the HPV vaccine; ...

Phase N/A

Resistance Testing to Improve Management of Virologic Failure in Sub-Saharan Africa

STUDY PROCEDURES FOR PARTICIPANTS RANDOMIZED TO STANDARD OF CARE ARM Visit 1-SOC: Baseline Visit for Standard of Care Participants At Study Visit 1, participants randomized to the SOC will complete the baseline questionnaire to collect sociodemographic, HIV clinical and treatment history, self-reported ART medication adherence, quality of life, and resource ...

Phase N/A

Pneumococcal Vaccines in Patients With Asthma

Patients will be randomized into either PCV13 and PPSV23 (Experimental) or PPSV23 alone (Active comparator). At the Week 0 time point, the patients will receive either PCV13 (Experimental) or PPSV23 (Active comparator) and undergo a blood draw of 5ml for assessment of pre-vacation serotype titers. The Active Comparator group will ...

Phase

Potlako: A Programmatic Intervention to Improve Access to Timely Oncology Care

Diagnostic and treatment delays contribute substantially to disparities in cancer morbidity and mortality between low- and middle- income countries (LMICs) and high-income countries. Individuals present with advanced stage disease resulting in minimal chance for cure or long-term survival. The Potlako project will implement and evaluate a multifaceted intervention to test ...

Phase N/A