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Vaccines Clinical Trials

A listing of Vaccines medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (30) clinical trials

This is a study to assess the pharmacokinetics (PK) of tedizolid phosphate and its active metabolite, tedizolid, and the safety of tedizolid phosphate following administration of a single IV (Part A) or oral suspension (Part B) administration to hospitalized participants ages 6 to less than 12 years (Groups 1 and ...

Phase

The goal of this study is to compare changes in the female genital tract in women diagnosed with bacterial vaginosis (BV) before and after treatment and to compare differences in the female genital tract in adolescent and adult women. Women with BV have an increased risk of acquiring HIV and ...

Phase

Safety of 4Fluart Intradermal Suspension for Injection (Influenza Vaccine Whole-virion Inactivated Adjuvanted) in Adult Subjects

Healthy volunteers (male and female) aged 18-59 years will be enrolled into the study by signing subject information leaflet and informed consent form. After screening them, subjects complying with inclusion and exclusion criteria will be included in the study, randomised and vaccinated with one of the investigational medicinal products assigned ...

Phase

Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)

Malaria remains a major public health threat despite regulatory approval of a partially effective pre-erythrocytic malaria vaccine. There is an urgent need to accelerate the development of a more effective multi-stage vaccine. Controlled human malaria infection (CHMI) has been shown to be an important tool for the assessment of the ...

Phase

Pharmacokinetics of Efavirenz in the Presence of Rifampicin and Isoniazid

Protocol Number: SSAT 062 EudraCT Number: 2014-002608-26 Name of Investigational Product: Sustiva/Stocrin/Atripla; Rifinah or local generic 300/150 Name of active ingredients: Efavirenz/ rifampicin/ isoniazid Study title:Steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily in the presence of rifampicin and isoniazid (Rifinah or the local generics) Name of Non Investigational ...

Phase

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

Protocol Number: SSAT069 EudraCT Number: 2015-004799-30 Name of Investigational Product: Microgynon 30®; Evotaz® Name of active ingredients: Ethinylestradiol, levonorgestrel; atazanavir, cobicistat Study title: The effect of atazanavir/cobicistat on the pharmacokinetics of an oral contraceptive containing ethinylestradiol and levonorgestrel (Microgynon 30®) in healthy women Phase of study: Phase I Objectives: The ...

Phase

A Phase Ib Trial of MSP 3 LSP in 1-2 Year Old Children in Burkina Faso

The study is a single centre randomized controlled and blinded study (observer blind). It will be conducted at the CNRFP Vaccinology unit located in Balonghin. Children in the catchments area within the 1-2 years age group, whose parents consent will be screened to randomise 45 eligible participants. Two MSP 3 ...

Phase

Safety of Recombinant Hybrid GMZ 2 [GLURP + MSP 3] Blood Stage Malaria Vaccine

Background. GMZ2 is a recombinant hybrid of the Glutamate Rich Protein (GLURP) and the Merozoite Surface Protein 3 (MSP 3).This product has been developed at Sate Serum Institute in Denmark and Bacth released by Henogen of Belgium. The phase Ia trial in malaria naive volunteers is currently ongoing in Germany, ...

Phase

Safety and Immunogenicity of Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545])

This will be a randomized controlled trial to evaluate the Safety and Immunogenicity of recombinant pichia pastoris blood stage malaria vaccine Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) versus tetanus toxoid, in healthy Malian adults in Bandiagara. A phase Ia trial is currently ongoing and its interim results will be used to ...

Phase