Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Post-Partum Depression Clinical Trials

A listing of Post-Partum Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found (34) clinical trials

Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries

Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal tears. These tears can have a significant impact on women's quality of life in the short and long term. One of the most distressing immediate complications of this severe perineal injury is perineal pain. Women can also experience …

Phase

Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression

Postpartum depression is a non-psychotic major or minor depressive episode that occurs during pregnancy or within 12 months of post-partum period. The nature of symptoms is same as depressive episode characterized by depressed mood, anxiety, sleep difficulties, suicidal thoughts, tiredness and diminished interest in pleasurable activities. Severe maternal depression affects …

Phase

PREPP: Preventing Postpartum Depression

Of the nearly 4 million mothers delivering live births each year in the United States, approximately 560,000 or 14% will develop major or minor depression within the first four months postpartum, when the rate peaks. This number dwarfs prevalence rates for gestational diabetes (2-5%) and is comparable to preterm birth …

Phase N/A

Reducing Maternal Depression and Promoting Infant Social-Emotional Health & Development

To address the life course needs of depressed mothers and their infants, brief, accessible, and integrated interventions that target both maternal depression and specific nurturing parent behaviors demonstrated to improve infant social-emotional communication outcomes are needed. In prior programmatic research, two separate web-based, remote coaching interventions for: (a) parent nurturing …

Phase N/A

Mother and Late Preterm Lactation Study

Breastfeeding has various benefits for the mother and infant. It has the capability of reducing the risk of short term and long term problems for the infant, such as gastroenteritis, respiratory infections, type II diabetes and obesity, and of providing benefits for neurodevelopment. Breast milk offers even greater benefits for …

Phase N/A

Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression

The investigators will conduct a 6-week, randomized, double-blind, placebo-controlled trial of celecoxib as an add-on treatment to the mood stabilizer among women with bipolar I or II postpartum depression. Women who are taking a mood stabilizer for treatment of bipolar disorder in the postpartum treatment will receive either a placebo …

Phase

Postnatal Depression Attachment and Self-defining Memories

In this context, it seems important to look for if there are specificities concerning the profiles of attachment and the self-defining memories at the patients suffering from postnatal depression. Especially as the current literature approaches only little this subject of public health. To analyze these specificities, two groups (group postnatal …

Phase N/A

Video-Feedback Interaction Guidance for Improving Interactions Between Depressed Mothers and Their Infants ("VID-KIDS")

Background & Rationale: Affecting ~19% of mothers, postpartum depression (PPD) reduces maternal sensitivity and positive responsiveness to infant cues and bids for caring attention. Infants perceive these behaviours as stressful which stimulates the hypothalamic pituitary adrenal axis, triggering cortisol release which, at persistently elevated levels, inhibits neurogenesis during critical periods …

Phase N/A

An Observational Study of Post-cesarean Delivery Respiratory Patterns Using a Non-invasive Minute Ventilation Monitor (Exspiron System)

The purpose of this study is to evaluate the breathing patterns of women who undergo cesarean delivery with spinal or epidural morphine for post-operative pain control in the first day after surgery. Some women who undergo cesarean delivery may be at risk for respiratory complications related to opiate administration for …

Phase N/A

Group CBT for PPD in the Public Health Setting

In addition to its effects on maternal health, PPD can adversely affect mother-infant attachment, parenting, and the development and health of her children. The negative effects of PPD on offspring can include an increased risk of insecure attachment, poorer cognitive, language, and behavioral development, as well as an increased risk …

Phase N/A