Post-Partum Depression Clinical Trials

The purpose of this study is to test an investigational drug called SAGE-547 (Allopregnolone) to determine if it is safe and has any effect on moderate and/or severe postpartum depression. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA).

To determine if SAGE-547 Injection infused intravenously for 60 hours reduces depressive symptoms in subjects with postpartum depression (PPD) compared to placebo injection

The purpose of the study is to examine how mother's mental health experiences might influence brain function in response to her infant and how this might be related to the parent-infant relationship. There will be 2 study visits over 7 to 10 days. The first visit is 3 to 4 ...

Anxiety? Fear? Despair? After childbirth is not your fault. It Could Be Postpartum Depression. Learn more about a research study in women with severe postpartum depression. Postpartum depression is a biological complication of pregnancy. Symptoms may include anxiety, fear, or despair and should not be ignored. If you frequently feel ...

Now enrolling for a postpartum depression research study for women in San Antonio, TX. Qualified participants receive study-related medical care and medication provided at no cost. Transportation may be provided for those who require assistance.

Disturbances in mother-infant relationship in depressed mothers negatively influence the child's development. There are a number of efficient treatments for postnatal depression including antidepressant medication, psychotherapy and psychosocial interventions. Tele-health and mobile health is a novel and emerging field in psychiatric and psychological care and treatment of mental health difficulties, ...

Despite the high prevalence of maternal depression in Pakistan, research on psychosocial interventions is limited. We will test the effectiveness of a telephone based intervention program called Learning through Play plus Interpersonal Psychotherapy (LTP Plus) that can be used by non-specialists, including trained graduates, mothers and lay health workers with ...

Enhancements to Mothers and Babies are warranted to address the mental health of both parents, via the home visitation service delivery model where many of the most at-risk families enter into provider-client relationships during their child's infancy and early childhood. Previous postpartum depression preventive interventionsincluding MBhave neglected to intervene with ...

Postpartum depression (PPD) affects up to 20% of women and has profound effects on mothers and their infants. Indeed, the cost of one case of PPD is estimated to exceed $150,000. Unfortunately, fewer than 15% of women with PPD receive evidence-based care and this is at least partly due to ...

Study Aims: Aim #1 is to conduct a superiority trial that compares the efficacy of MB delivered by paraprofessional home visitors versus usual care (i.e., home visiting without MB) on patient-reported outcomes, including depressive symptoms, quality of life, parenting practices, engagement in pleasant activities, and relationship with one's partner. Aim ...