Renal Cell Carcinoma Clinical Trials

A listing of Renal Cell Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 41 clinical trials
Concurrent Neoadjuvant Chemoradiotherapy Plus Durvalumab (MEDI4736) in Resectable Stage III NSCLC

Combination treatment of Durvalumab with chemoradiotherapy is ongoing for head/neck cancer, renal cell carcinoma, melanoma, and non-small cell lung cancer (NCT02318771) and pancreatic cancer

  • 0 views
  • 23 Jan, 2021
  • 1 location
Niraparib in Combination With Cabozantinib (XL184) in Patients With Advanced Urothelial Cancer (NICARAGUA)

activity for cabozantinib in patients with advanced renal cell carcinoma and metastatic castration-resistant prostate cancer (mCRPC). Furthermore, in preclinical models of urothelial carcinoma (UC) of the

transitional cell carcinoma
neutrophil count
metastatic cancer
programmed cell death protein 1
oophorectomy
  • 46 views
  • 26 Jan, 2021
  • 12 locations
Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma

molecule multi-kinase inhibitor of VEGFR, PDGFR and RAF with demonstrated activity in the treatment of renal cell cancer (9). Preclinical studies suggest that the combination of Sorafenib with

small molecule
doxorubicin
anthracyclines
monoclonal antibodies
measurable disease
  • 13 views
  • 07 Nov, 2020
  • 1 location
Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Substudy 03A is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy

systemic therapy
carcinoma
lenvatinib
pembrolizumab
major surgery
  • 0 views
  • 13 Jul, 2021
  • 22 locations
Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B)

Substudy 03B is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy

carcinoma
tyrosine
monoclonal antibodies
growth factor
lenvatinib
  • 0 views
  • 13 Jul, 2021
  • 23 locations
Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer

This is an open label, prospective, trial that begins with a phase Ib safety run-in followed by a phase II expansion cohort.

adenocarcinoma
platelet count
gilbert's syndrome
metastasis
neutrophil count
  • 0 views
  • 26 Jan, 2021
  • 1 location
GEN1029 (HexaBody -DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors

The purpose of the trial is to evaluate the safety of GEN1029 (HexaBody-DR5/DR5) in a mixed population of patients with specified solid tumors

measurable disease
metastasis
cancer
renal function
metastatic cancer
  • 212 views
  • 24 Jul, 2021
  • 6 locations
Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611

IV administration of pembrolizumab, in subjects with non-HCC liver metastases from BC, CRC, gastroesophageal cancer (GEC), melanoma, NSCLC, RCC in Part 1 Group A, and subjects with HCC with and

liver tumor
antiviral therapy
epidermal growth factor receptor
liver metastasis
antiviral drugs
  • 0 views
  • 10 Jun, 2021
  • 65 locations
Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their …

carcinoma
monoclonal antibodies
measurable disease
lung carcinoma
triple negative breast cancer
  • 89 views
  • 06 Jul, 2021
  • 11 locations
A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer

This research study is done to test the safety of the new drug selitrectinib in children and adults with cancer having a change in a particular gene (NTRK1, NTRK2 or NTRK3). The drug may treat cancer by interfering with the effect of the NTRK genes on cancer growth. The study …

fibrosarcoma
cancer
experimental drug
kidney function tests
primary tumor
  • 1310 views
  • 27 Jul, 2021
  • 79 locations