Ovarian Function Clinical Trials

A listing of Ovarian Function medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 211 clinical trials
Autologous Ovarian Tissue Transplantation

Chemotherapy and radiation for cancer and other conditions can cause infertility. Several centers around the world are cryopreserving ovarian tissue from these patients though an experimental protocol, including the Fertility Preservation Program in Pittsburgh (protocol PRO08050491). The objective of this study is to study the efficacy and safety of autologous …

cancer
ovarian failure
infertility
fertility preservation
  • 450 views
  • 04 Jun, 2022
  • 1 location
Hyperthermic Intraperitoneal Chemotherapy for Recurrent Ovarian Cancer

This is a phase I prospective study with the primary objective to compare the efficacy and safety of Surgical cytoreduction (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in treatment of recurrent ovarian, primary peritoneal or fallopian tube cancers. Eligible patients consenting to this protocol will undergo their scheduled surgical procedure. After …

recurrent ovarian cancer
primary peritoneal carcinoma
carcinoma
ovarian epithelial carcinoma
intraperitoneal chemotherapy
  • 31 views
  • 12 May, 2022
  • 1 location
Living WELL: A Web-Based Program for Ovarian Cancer Survivors

The purpose of this study is to determine the efficacy of a group-based and web-delivered psychosocial intervention for ovarian cancer survivors (Mindful Living [ML]) compared to a health promotion condition (Healthy Lifestyles [HL]) in increasing health related quality of life (HRQOL) and decreasing perceived stress, depressive mood (primary aims), anxiety, …

peritoneal cancer
fallopian tube
cancer chemotherapy
tumor markers
ovarian epithelial carcinoma
  • 4 views
  • 12 May, 2022
  • 3 locations
Apatinib Combined With Abraxane and Carboplatin or Cisplatinum as First-line Treatment for Epithelial Ovarian Cancer

This monocentric, prospective, observational study will evaluate the safety and efficacy of apatinib in combination with albumin binds paclitaxel and carboplatin or cisplatinum as first-line treatment for stage II-IV epithelial ovarian cancer followed by apatinib maintenance therapy in routine clinical practice. Eligible patients will be followed for approximately 20 months.

paclitaxel
apatinib
carboplatin
ovarian carcinoma
carcinoma
  • 0 views
  • 26 Jan, 2021
  • 1 location
MESO-CAR T Cells Therapy for Relapsed and Refractory Epithelial Ovarian Cancer

The goal of this clinical trial is to study the feasibility and efficacy of anti-MESO antigen receptors (CARs) T cell therapy for relapsed and refractory epithelial ovarian cancer.

ovarian epithelial cancer
ovarian epithelial carcinoma
cancer of the ovary
  • 24 views
  • 02 Feb, 2022
  • 1 location
IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC (IMPACT)

The study will be conducted in women with advanced (stage IIIa-IV) ovarian cancer of the histologic subtype high grade serous carcinoma (HGSOC) who are going through a diagnostic laparoscopy. They will recieve treatment with a study agent for 10-14 days before surgery. They will be allocated to different study groups …

peritoneal cancer
olaparib
metastasis
serous cystadenocarcinoma
cancer of the ovary
  • 2 views
  • 27 Feb, 2022
  • 2 locations
Niraparib Maintenance in Patients With Advanced Ovarian Cancer at Neoadjuvant Setting

This study aims to evaluate the effects of niraparib in those who have received neoadjuvant chemotherapy and subsequent interval debulking surgery, with or without hyperthermic intraperitoneal chemotherapy, and would also explore if there are any biomarkers, other than BRCA / HRD status and platinum sensitivity, that may help to identify …

tumor debulking
parp inhibitor
interval debulking surgery
primary peritoneal carcinoma
carcinoma
  • 0 views
  • 06 Oct, 2021
  • 1 location
EP0057 in Combination With Olaparib in Advanced Ovarian Cancer

EP0057-201 is a Phase 2A/B adaptive design study. Phase 2A will test EP0057 in combination with Olaparib and Phase 2B, the randomised part of the study, will test EP0057 in combination with Olaparib against SOC chemotherapy. When EP0057 is combined with Olaparib, it is envisaged that the combination should improve …

line of therapy
olaparib
parp inhibitor
neutrophil count
measurable disease
  • 11 views
  • 27 Apr, 2022
  • 16 locations
Olaparib Monotherapy and Olaparib + Pembrolizumab Combination Therapy for Ovarian Cancer

To evaluate the efficacy and safety of preoperative olaparib monotherapy and preoperative olaparib plus pembrolizumab combination therapy in patients with untreated stage III, IV high-grade serous or Grade 3 endometrioid ovarian cancer with Homologous Recombination Deficiency (HRD) positivity.

  • 0 views
  • 12 Feb, 2021
  • 3 locations
ROCKIF Trial: Re-sensitization of Carboplatin-resistant Ovarian Cancer With Kinase Inhibition of FAK

The purpose of the study is to investigate the combination VS-6063, carboplatin, and paclitaxel. in the treatment of patients with ovarian cancer. The study will evaluate whether this regimen is safe. The study will also evaluate whether the regimen can reduce the amount of cancerous cells in your body. If …

paclitaxel
carboplatin/paclitaxel
carcinoma
monoclonal antibodies
endocrine therapy
  • 20 views
  • 15 Feb, 2022
  • 1 location