Ovarian Function Clinical Trials

A listing of Ovarian Function medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 15 clinical trials
Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer (RIBOLARIS)

This is an open-label, multicenter international trial in men and women with primary operable HR+/HER2-, ki67≥20%, grade 2 or 3 and stage II breast cancer to evaluate safety and long-term efficacy of a non-chemo treatment in patients biologically responders to neoadjuvant ribociclib and letrozole. This study aims to evaluate whether …

  • 0 views
  • 04 Oct, 2022
  • 17 locations
Ovarian Needle Puncture for Follicle Activation in IVF Patients With Diminished Ovarian Reserve

Premature ovarian insufficiency (POI), is cessation of ovarian function characterized by hypergonadotropic amenorrhea and hypoestrogenic syndrome before 40 years of age. About 1% of women

  • 5 views
  • 13 Oct, 2022
  • 1 location
Density Lowering Effect of Ovarian Function Suppression in Premenopausal Breast Cancer Patients Who Had no Density Change With One Year of Tamoxifen Treatment

DELFINO tial is designed to investigate the role of "OFS add on to TMX ", based on MMG density as a surrogate marker in premenopausal women Premise - MMG density as a surrogate marker of hormone therapy Assumption - "Add on OFS to TMX" would have further decrease of density …

hormone therapy
endocrine therapy
  • 3 views
  • 23 Oct, 2022
Clinical Observation on Kuntai Capsule in Treating Early-onset Ovarian Hypofunction

To evaluate the efficacy and safety of Kuntai capsule alone or combined with hormone therapy in improving ovarian function in POI patients (including subclinical stage).

estrogen
follicle stimulating hormone
ovarian failure
hormone therapy
estradiol
  • 0 views
  • 07 Oct, 2022
  • 6 locations
Ultrasound Characterization of Ovarian Follicle Dynamics During Weight Loss

The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women with irregular menstrual cycles and/or polycystic ovary syndrome (PCOS).

multivitamins
insulin
reproductive hormones
diabetes
hormonal contraception
  • 284 views
  • 16 Oct, 2022
  • 1 location
Inositol Supplementation to Treat Polycystic Ovary Syndrome: A Double Blind Dose Ranging RCT (INSUPP-PCOS) (INSUPP-PCOS)

To determine if Inositol, a dietary supplement, will improve ovarian and adrenal androgen excess in women with Polycystic Ovarian Syndrome(PCOS).

testosterone
free androgen index
hyperandrogenism
testosterone level
inositol
  • 847 views
  • 23 Oct, 2022
  • 1 location
Phase 3,Single Arm,Open-Label Study Evaluating Ovarian Suppression Following 3 Month Leuprolide Acetate For Injectable Suspension (TOL2506) in Combination With Endocrine Therapy in Premenopausal Subjects With Hormone-Receptor-Positive (HR+),Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer (OVELIA)

This is a phase 3, single arm, open-label study evaluating the effectiveness of TOL2506 to suppress ovarian function in premenopausal women with HR+, HER2-negative breast cancer. The study will

her2/neu-negative breast cancer
anastrozole
letrozole
exemestane
HER2
  • 1 views
  • 28 Oct, 2022
  • 31 locations
Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression

Background Some women who had depression in the perimenopause may have mood symptoms again if they stop estrogen therapy. Estrogen acts in the brain and other tissues by binding to at least three types of estrogen receptors. One of these receptors, estrogen receptor beta may affect anxiety and depression. The …

blood tests
mood symptoms
structured clinical interview
depressed mood
depression
  • 232 views
  • 04 Oct, 2022
  • 1 location
Multi-institutional Study to Increase Breast Conserving Surgery (BCS) Rate With Personalized Neoadjuvant Strategy in ER Positive and HER2 Negative Breast Cancer Patients for Whom BCS is Not Feasible

In ER+ and HER2- breast cancer(BC) patients for whom BCS is not feasible, we investigate the rate of BCS can be increased while decreasing unnecessary chemotherapy thru selective neoadjuvant chemotherapy or neoadjuvant endocrine therapy using tools of nodal status, Ki-67, and multigene assay(Mammaprint)

her2/neu-negative breast cancer
letrozole
ki-67
endocrine therapy
HER2
  • 0 views
  • 27 Oct, 2022
  • 1 location
A Pilot Study to Test Rapid Acquisition of Point of Care Ultrasound for Various Applications

Summary Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images. The study will use a newly developed acquisition method and post-processing technique to create three dimensional image models of the abdomen …

3d ultrasound
pelvic ultrasound
safety issues
imaging techniques
Accepts healthy volunteers
  • 861 views
  • 25 Oct, 2022
  • 1 location