Prostate Cancer Clinical Trials

A listing of Prostate Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 80 clinical trials
Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for OligoRecurrenT Prostate Cancer (VA STARPORT)

The primary goal of this study is to determine if adding PET-directed local therapy improves disease control compared to standard systemic therapy alone in Veterans with oligorecurrent prostate

  • 4 views
  • 12 Aug, 2022
  • 16 locations
A Study of EPI-7386 in Combination With Abiraterone Acetate Plus Prednisone, or Apalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC)

The purpose of this study is to determine safety, including dose limiting toxicities, and the recommended phase 2 dose (RP2D) of EPI-7386 in separate combinations with (a) abiraterone acetate plus prednisone or prednisolone (AAP) and (b) apalutamide (dose-finding) and to determine the antitumor activity of EPI-7386 in separate combinations with …

  • 0 views
  • 11 Aug, 2022
  • 4 locations
Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

The purpose of this study is to look at the effect that the study drug OPC has on AGE levels in patients with prostate cancer.

orchiectomy
adenocarcinoma
metastatic prostate cancer
adenocarcinoma of prostate
gonadorelin
  • 1 views
  • 09 Aug, 2022
  • 1 location
The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

than men. Women have higher amounts of zolpidem in their body that may persist after waking. Drug exposure may also depend on male hormones that change during prostate cancer therapy. Researchers want

definitive treatment
cancer treatment
blood test
testosterone
cancer
  • 5 views
  • 10 Aug, 2022
  • 1 location
Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

To determine the dose, safety, radiation dosimetry and efficacy of 177Lu-rhPSMA-10.1 in participants with PSMA-expressing metastatic castrate resistant prostate cancer.

  • 0 views
  • 08 Aug, 2022
  • 1 location
PINPOINT Feasibility Study

tissue in patient having post-operative prostate cancer radiotherapy. Structure visualisation on MRI and TPUS will be compared to current standard computer tomography (CT) and cone-beam computer

  • 0 views
  • 09 Aug, 2022
  • 1 location
A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D[s]) of JNJ-69086420 in Part 1 (Dose Escalation) and to determine safety and and preliminary signs of clinical activity at the RP2D(s) in Part 2 (Dose Expansion).

administration intravenous
adenocarcinoma
cancer
chemotherapy regimen
  • 10 views
  • 11 Aug, 2022
  • 5 locations
Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)

. This may be true for many types of cancer, including castration-resistant prostate cancer (CRPC). Objective To test if the combination of the drugs BN-brachyury

nilutamide
advanced malignant solid tumor
androgens
flutamide
bilateral orchidectomy
  • 21 views
  • 10 Aug, 2022
  • 1 location
Pharmacokinetics of IA and IV Ga68-PSMA-11 Infusion

Prostate-specific membrane antigen (PSMA) agents have shown promise in detecting and treating prostate cancer. Gallium-68-labeled PSMA-11 (68Ga-PSMA-11) is a radioactive agent that binds to

  • 0 views
  • 10 Aug, 2022
  • 1 location
Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate Cancer

resistant prostate cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as decitabine/cedazuridine, work in different ways to stop the growth of tumor cells, either by

  • 0 views
  • 11 Aug, 2022
  • 1 location