Prostate Cancer Clinical Trials

This is a randomized, double-blind, placebo-controlled, multicenter phase III study. The study population will consist of approximately 1300 subjects with metastatic hormone sensitive prostate cancer (mHSPC), who will be randomized (1:1 ratio) to receive 600 mg (2 x 300 mg tablets) of darolutamide (ODM-201)/placebo twice daily with food, equivalent to ...

The purpose of this study is to assess the safety and efficacy of BAY1841788 (ODM-201) in patients with non-metastatic castration-resistant prostate cancer. For Study Locations, Click Here

The objective of this randomized phase III open label trial is to assess if upfront combination of enzalutamide and Ra223 improves radiological progression-free survival compared to enzalutamide single agent in asymptomatic or mildly symptomatic castration resistant prostate cancer patients metastatic to bone. For Study Locations, Click Here

The purpose of the study is to assess the efficacy and safety of BAY1841788 (darolutamide (ODM-201)) in combination with standard androgen deprivation therapy (ADT) and docetaxel in patients with metastatic hormone sensitive prostate cancer. For Study Locations, Click Here

A Multi-Center, Open Label, Phase 2b study, Evaluating the safety, tolerability and efficacy of Targeted Intraprostatic Administration of XXXXX to treat men with histologically proven, clinically significant, localized, Low-to Intermediate-Risk Prostate Cancer that is associated with an MRI Leasion

The ATR(ataxia-telangiectasia and Rad3 related protein) inhibitor BAY1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas. The purpose of the proposed trial is to evaluate the safety and tolerability of BAY1895344, and to identify the maximum tolerated dose of BAY1895344 that could be safely given ...

The MR-guided ExAblate Focused Ultrasound study is being conducted to assess the safety and effectiveness of an investigational device for the treatment of prostate cancer. The ExAblate treatment is a focal treatment where a small portion of the prostate is treated, only where the cancer is located. The study will ...

The main purpose of this study is to see if Niraparib is useful to treat men with advanced prostate cancer. The safety of niraparib will also be studied.

The purpose of this study is to assess enzalutamide plus leuprolide in patients with high-risk nonmetastatic prostate cancer progressing after radical prostatectomy or radiotherapy or both.

Winthrop University Hospital Clinical Trials Center is conducting this clinical research study for men ages 18 and older who have biopsy proven Prostate Cancer. Metformin therapy for patients diagnosed with Prostate Cancer who have been treated with either radiation therapy or surgery who have indicators of high risk disease, or ...