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Autonomic Nervous System Clinical Trials

A listing of Autonomic Nervous System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (180) clinical trials

This is a multi-site, placebo-controlled, double-blind, randomized-withdrawal study evaluating the durability of clinical benefit of a study drug for patients with symptomatic neurogenic orthostatic hypotension. This study has a duration of up to 36 weeks, consisting of 5 periods:  Screening Period: up to 4 weeks duration;  Open-Label Titration Period (Titration ...


The purpose of this study is to collect retrospective real-world clinical data to assess the performance including efficacy and safety of CD HORIZON® LEGACY™ PEEK Rod Spinal System used as supplemental fixation for a posterior interbody fusion cage in subjects who have undergone a posterior non-cervical spinal fusion procedure for ...

Phase N/A

A research study is evaluating an investigational treatment for chemotherapy induced peripheral neuropathy in patients with colorectal cancer (CRC).

Phase N/A

Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury

Interruption of sympathetic cardiovascular autonomic regulation following spinal cord injury (SCI) is associated with significantly reduced plasma norepinephrine (NE) levels, hypotension and orthostatic hypotension (OH), particularly in individuals with high cord lesions. Although the incidence of hypotension is reported to be as high as 70% in persons with cervical lesions ...


Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy

This is a non-randomized, phase I, escalating single dose study to assess the safety of the gene transfer vector scAAV9/JeT-GAN through intrathecal delivery to the brain and spinal cord of patients with Giant Axonal Neuropathy (GAN, OMIM No.256850). The primary objective of this study is to assess the safety of ...


The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorders. The evaluations will help determine if the participant meets criteria for participation in research protocols of the Pediatric and Developmental Neuroscience Branch ...

Phase N/A

Progressive Resistance Training in Acute Spinal Cord Injury

The trial and recruitment will be conducted at the Queen Elizabeth National Spinal Injuries Unit (QENSIU), Glasgow. Individuals with tetraplegia and upper limb weakness will be randomly allocated to receive either a tailored progressive resistance training (PRT) programme alongside usual care or usual care alone. Up to 30 participants admitted ...

Phase N/A

The SNAP Trial: SPRINT Peripheral Nerve Stimulation for the Treatment of Neuropathic Post-Amputation Pain

The purpose of this study is to determine if pain can be relieved by delivering small amounts of electricity (called "electrical stimulation") to the nerves in an individual's amputated leg.This study will involve the use of a Peripheral Nerve Stimulation (PNS) System that is made by SPR Therapeutics (the sponsor ...

Phase N/A

The Study of Acupuncture on Vascular and Functional Neuroimaging in Parkinson's Disease Patients With Sleep Disorders

Neuroimaging assessment:Subjects are keeping awake, resting flat on the examination table, using rubber earplugs to reduce noise, using foam headbands to fix head movement artifacts, closing eyes to calm breathing, fixing the head and minimizing head and other parts of the initiative and passive exercise.At the same time, it is ...

Phase N/A

Evaluation of the Interest of Hypno-relaxation During Somatosensory Evoked Potentials

Somatosensory evoked potentials corresponds to a neurophysiological exam that studies the functioning of the sensitivity pathways. It is often complementary to the imaging examination (MRI or scanner) and the electroneuromyogram which studies only the peripheral part of the sensory and motor pathways while the somatosensory evoked potentials are interested in ...

Phase N/A