Rectal Cancer Clinical Trials

A listing of Rectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 165 clinical trials
Induction Chemotherapy for Locally Recurrent Rectal Cancer (PelvEx II)

This is a multicentre, open-label, parallel arms, phase IIII study that randomises patients with locally recurrent rectal cancer in a 1:1 ratio to receive either induction chemotherapy followed

  • 0 views
  • 07 Oct, 2022
  • 8 locations
Non-Operative Management and Early Response Assessment in Rectal Cancer (NOM-ERA)

The investigators' data from a phase I study of short course radiation therapy followed by chemotherapy showed 74% complete clinical response (cCR). Given the promising response rate, the investigators are evaluating short course radiation therapy (SCRT) followed by chemotherapy in a multi-institution phase II trial to validate the cCR rate …

  • 0 views
  • 07 Oct, 2022
  • 4 locations
Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer

patients with locally advanced rectal cancer treated with short-course radiotherapy sequential Tislelizumab combined with CapeOX (group A) versus short-course radiotherapy sequential CapeOX (group B). A

  • 0 views
  • 04 Oct, 2022
  • 1 location
The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Locally Advanced Rectal Cancer (TORCH)

The study evaluates the combination of immunotherapy of PD-1 antibody and neoadjuvant short-course radiotherapy in locally advanced rectal cancer (LARC). Patients are randomly assigned into two

  • 0 views
  • 04 Oct, 2022
  • 4 locations
High-volume and Low-volume Water Transanal Irrigation for the Management of Low Anterior Resection Syndrome. A Crossover Randomized Controlled Clinical Trial. (HiLoV_TAI)

The aim of this study is to investigate whether the high-volume transanal irrigation (TAI) performed by the Peristeen Plus® system is superior to the low-volume TAI performed by standard 250ml water enema for the treatment of Low Anterior Resection Syndrome (LARS).

  • 0 views
  • 14 Oct, 2022
  • 2 locations
Pathway of Low Anterior Resection Syndrome Relief After Surgery: a Feasibility Study (POLARiS)

Currently, no standard exists for the treatment and management of Low Anterior Resection Syndrome (LARS)- a common disorder that affects patients who have had part of their bowel removed due to colorectal cancer. Decisions about which treatment patients receive is at the discretion of local clinicians, leading to a variation …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

advanced rectal cancer and low risk for local failure

xelox
capecitabine
oxaliplatin
folfox regimen
adenocarcinoma
  • 0 views
  • 04 Oct, 2022
  • 1 location
Multicentric Phase II-III Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma After a Favorable Response to Induction Chemotherapy (GRECCAR14)

Locally advanced rectal carcinoma raise the issue of both the oncological control, local and general, and the therapeutic morbidity. Surgery alone can cure only one out of two patients

proctectomy
irinotecan
carcinoma
capecitabine
oxaliplatin
  • 0 views
  • 23 Oct, 2022
  • 14 locations
Short-course Radiotherapy Versus Chemoradiotherapy, Followed by Consolidation Chemotherapy, and Selective Organ Preservation for MRI-defined Intermediate and High-risk Rectal Cancer Patients

incorporates several novel and innovative aspects to further optimize multimodal rectal cancer treatment, partly established by our preceding CAO/ARO/AIO-04 and CAO/ARO/AIO-12 randomized trials: (1) patient

  • 6 views
  • 04 Oct, 2022
  • 72 locations
Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone (REPCA)

The purpose of the study is to determine if short-term outcomes of rectal resections after full bowel preparation (mechanical bowel preparation plus oral antibiotics) are superior to rectal resections with only mechanical bowel preparation.

adenocarcinoma
proctectomy
  • 1 views
  • 18 Oct, 2022
  • 7 locations