Rectal Cancer Clinical Trials

A listing of Rectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 673 clinical trials
Featured trial
  • 08 Nov, 2020
  • 1 location
Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer

advanced rectal cancer. The hypothesis is 3-year disease-free survival in TNT group was non-inferior to that in CRT group.

pelvic mri
adenocarcinoma of rectum
  • 21 Jul, 2021
  • 1 location
Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive for postoperative circulating tumour DNA with vs. without capecitabine.

  • 24 Jan, 2021
Dendrobium Huoshanense Suppository in Rectal Cancer

To evaluates the role of Dendrobium Huoshanense Suppository for radiation proctitis in locally advanced rectal cancer treated by capecitabine and irinotecan based neoadjuvant chemoradiation.

  • 22 Oct, 2021
Organ Preservation in Locally Advanced Rectal Cancer (PRONAR)

PRONAR trial aims to assess if treatment with organ preservation in stage II and III rectal cancer after a complete or almost complete response to neoadjuvant treatment is feasible and safe in

  • 25 Feb, 2022
  • 1 location
Induction Chemotherapy for Locally Recurrent Rectal Cancer (PelvEx II)

This is a multicentre, open-label, parallel arms, phase IIII study that randomises patients with locally recurrent rectal cancer in a 1:1 ratio to receive either induction chemotherapy followed

  • 07 Oct, 2022
  • 8 locations
Extended Resection for Rectal Cancer With Neoadjuvant Radiotherapy

Preoperative neoadjuvant therapy has become the guideline-recommended standard treatment for patients with locally advanced or mid-to-low rectal cancer with suspected regional lymph node

  • 10 Mar, 2022
  • 1 location
Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery (PREPACOL2)

This study aims to demonstrate that a preoperative combination of mechanical bowel preparation and oral antibiotics, before elective laparoscopic rectal cancer surgery, is associated with a

  • 27 May, 2022
  • 1 location
Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer (RECTUM2015)

Phase II, Multicenter, Open-label, Randomized Study evaluating neoadjuvant chemotherapy (FOLFOX4) in patients with stage II and III colorectal cancer with standard chemoradiation Defined by Magnetic Resonance Imaging

  • 30 May, 2022
  • 1 location
Non-Operative Management and Early Response Assessment in Rectal Cancer (NOM-ERA)

The investigators' data from a phase I study of short course radiation therapy followed by chemotherapy showed 74% complete clinical response (cCR). Given the promising response rate, the investigators are evaluating short course radiation therapy (SCRT) followed by chemotherapy in a multi-institution phase II trial to validate the cCR rate …

  • 07 Oct, 2022
  • 4 locations