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Staphylococcal Infections Clinical Trials

A listing of Staphylococcal Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (51) clinical trials

Early Identification and Effective Management of Pediatric Sepsis

We intend to enroll pediatric sepsis patients at four PICUs and divide them into two groups based on clinical outcomes: severe sepsis group (patients who progress into severe sepsis), sepsis group (patients who do not progress in to severe sepsis). We intend to perform predictive modeling using multivariable analyses of ...

Phase N/A

Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis

Sepsis remains a major challenge, even in modern intensive care medicine. The identification of the causative pathogen is crucial for an early optimization of the antimicrobial treatment regime in patients with sepsis. In this context, culture-based diagnostic procedures (e.g., blood cultures) represent the standard of care, although they are associated ...

Phase N/A

Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic Shock

In recent years, many studies have pointed out that bacterial toxin and cytokine storm are the main causes of shock and multiple organ failure in patients with sepsis. Endotoxin is the main vehicle for systemic inflammatory reaction caused by gram-negative bacteria which induce sepsis. Endotoxin binds to Toll- Like receptor ...

Phase N/A

Mitochondrial Function in Septic Patients

Aim #1 To investigate the prevalence, risk and correlation of the level of sepsis with mitochondrial dysfunction in sepsis patients Aim 1.1 To investigate the prevalence of mitochondria dysfunction among sepsis patients Hypothesis: Most of sepsis patients are affected by mitochondria dysfunction. Since there are many suspected cases of sepsis ...

Phase N/A

Effects of High-frequency Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis

This is a randomized, controlled, double-blind clinical trial. Thirty-six patients with a diagnosis of sepsis or septic shock in the experimental group (high frequency electrical stimulation) and sham group will be randomized. They will be evaluated in relation to muscle mass, peripheral muscle strength and functional status. They will also ...

Phase N/A

Ascorbic Acid and Thiamine Effect in Septic Shock

Sepsis is a complex disease involving life-threatening organ dysfunction caused by a dysregulated host response to infection and is still associated with unacceptably high mortality. Sepsis management should be undertaken as a medical emergency and focused on timely intervention, including early identification and treatment of infection through appropriate antimicrobial therapy ...

Phase

Ceftriaxone as Home IV for Staph Infections

The use of ceftriaxone for deep-seated Staphylococcal infections requiring prolonged IV treatment is a practice that has already evolved both locally and globally despite the absence of high-quality clinical data. Retrospective studies that support the use of ceftriaxone for this indication, including those that currently inform Infectious Diseases Society of ...

Phase

Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis

The present is an observational single centre no profit study. The duration is expected to be 12 months from September 2019. The study will be conducted by enrolling patients aged 18 to 80 years in intensive care with diagnosis of septic shock according to the Third National Consensus Definitions for ...

Phase N/A

Fast Assay for Pathogen Identification and Characterization

This study is a follow-up study of the first prospective study performed in 2017 in the same hospital. The ClinicalTrials.gov ID number of the previous study was NCT03025802.

Phase N/A

Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death

The aim of this observative, prospective study is to evaluate if and to what extent glycocalyx damage/microcirculation data at admission in the ICU as well as during ICU stay can be predictive of mortality and clinical course in patients presenting with the suspicion of sepsis/septic shock. Therefore, the enrollment of ...

Phase N/A