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Staphylococcal Infections Clinical Trials

A listing of Staphylococcal Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (43) clinical trials

Mitochondrial Function in Septic Patients

Aim #1 To investigate the prevalence, risk and correlation of the level of sepsis with mitochondrial dysfunction in sepsis patients Aim 1.1 To investigate the prevalence of mitochondria dysfunction among sepsis patients Hypothesis: Most of sepsis patients are affected by mitochondria dysfunction. Since there are many suspected cases of sepsis ...

Phase N/A

Effects of High-frequency Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis

This is a randomized, controlled, double-blind clinical trial. Thirty-six patients with a diagnosis of sepsis or septic shock in the experimental group (high frequency electrical stimulation) and sham group will be randomized. They will be evaluated in relation to muscle mass, peripheral muscle strength and functional status. They will also ...

Phase N/A

Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients

Sepsis and septic shock patients are considered to have a high risk of complications and death. Appropriate antimicrobial therapy plays an important role in determining outcomes in septic patients. However, pathophysiologic changes associated with critical illness have an impact on pharmacokinetics of antimicrobials. In addition, increasing bacterial resistance is also ...

Phase N/A

The Effect of Vitamin C Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock

AIM OF THE STUDY: The goal is to determine the effects on clinical course and outcome of patients with severe sepsis and septic shock treated with vitamin C, hydrocortisone and thiamine. BACKGROUND This study will be conducted in the intensive care unit of Department of Gastroenterology, University Medical Center (UMC) ...

Phase

Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis

Binding of TLRs to epitopes on microorganisms stimulates intracellular signaling, increasing transcription of proinflammatory molecules such as tumor necrosis factor (TNF-) and interleukin-1, as well as antiinflammatory cytokines such as interleukin-10. Macrophage dysfunction, as a component of immune suppression seen during trauma and sepsis, appears to be one of the ...

Phase N/A

Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis

Variables will be tested for their association with the outcome using Pearson chi-square test for categorical data and Mann-Whitney U test for numerical data. Comparison the different groups will be conducted by using Mann-Whitney U test for numerical data and using Pearson chi-square test for categorical data. The time course ...

Phase N/A

Echocardiography in Septic Shock

BACKGROUND: Echocardiography can provide evaluation of right or left ventricular dysfunction and volume status during resuscitation of patients with sepsis and septic shock and guide intravenous vasopressor and fluid therapy. While there are numerous echocardiographic studies regarding cardiac function and volume status in patients with established shock, there are none ...

Phase N/A

Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions

All German hospitals provide a set of routine data to federal adminsitration for reimbursement. This dataset includes all ICD-10-Codes (German adaption) as well as all procedure codes. This dataset is pseudonomized and risk adjusted for every individual case and afterwards feedbacked to each participating hospital including all accumulated data from ...

Phase N/A

Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock

Study will evaluate ability of passive leg raise test to predict fluid responsiveness in patients in septic shock, on vasopressors, using both the NICOM and FloTrac devices. An increase in CI, SVI, or Pulse Pressure of >10% in response to the passive leg raise will be considered a positive passive ...

Phase N/A

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients

Design- international, multicentre, crossover, cluster randomised controlled trial (x-cRCT) of eligible patients in participating ICUs using two 12-month interventional trial periods separated by a 3-month inter-period gap. An observational ecological assessment will be conducted in all ICU patients during one week of each month during the 3-month surveillance period before ...

Phase