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Cardiac Surgery Clinical Trials

A listing of Cardiac Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (303) clinical trials

A clinical study of the TAXUS® Liberté® Paclitaxel-Eluting Coronary Stent System which was previously approved by the FDA. Patient Inclusion Criteria: >years of age Patients that need a stent in the coronary arteries Patient Exclusion Criteria: Cannot receive the protocol required dual antiplatelet therapy Currently taking warfarin or similar anticoagulant ...

Phase

The treatment options this study will compare are: (1) Hybrid Coronary Revascularization [HCR] (a combination of surgery and catheter procedures to open up clogged heart arteries) and (2) Percutaneous Coronary Intervention [PCI] (catheter procedures alone to open up clogged heart arteries). There are no new or "experimental" procedures being tested ...

Phase

A Project to Improve the Diagnosis and Prognosis of Myocardial Injury Associated to Non Cardiac Surgery

Major adverse cardiovascular events are the leading cause of perioperative morbimortality in non-cardiac surgery. Perioperative myocardial infarction is usually asymptomatic, with a mortality around 10-12%. Myocardial Injury in Noncardiac Surgery (MINS), is defined as a myocardial injury that provokes a troponin increase due to myocardial ischemia. MINS is a predictor ...

Phase N/A

Intravenous Iron for Treatment of Anaemia Before Cardiac Surgery

Preoperative anaemia is common (30%) in patients awaiting cardiac surgery, and is associated with increased complications, ICU and hospital stay, and mortality. The extent of anaemia is worsened by haemodilution occurring with cardiopulmonary bypass and surgical bleeding (average blood loss 0.5-1.5 litres), which in turn impair end-organ blood flow and ...

Phase

Incidence and Outcome of Perioperative Myocardial Injury After Non-cardiac Surgery

Background: Worldwide more than 230 million surgical operations are performed each year. Despite advances in all fields of medicine, there is still a significant risk of death related to major non-cardiac surgical procedures. The observed 30-day mortality depends on patient- as well as procedural factors and ranges between 1% and ...

Phase N/A

Custodiol Versus Blood Cardioplegaia in Paediatric Cardiac Surgery

Hypothesis : Custodial is not inferior to blood cardioplegia in myocardial protection in paediatric cardiac surgery .. Methodology : Study design : Randomized controlled trial Data collection: All demographic data ,diagnosis ,procedure(type.CPB time ,crossclamp time) , surgeon and hospital course details . Computer generated randomisation into two groups based on ...

Phase

Human Fibrinogen Concentrate in Pediatric Cardiac Surgery

The goal of the study is to determine whether the use of Human Fibrinogen Concentrate (RiaSTAP) will decrease the need for component blood therapy in neonates and infants undergoing cardiopulmonary bypass. RiaSTAP will be administered after termination of Cardiopulmonary Bypass (CPB) at a dose of 70 mg/kg, in a prospective, ...

Phase

Effect of Low Dose ColchiciNe on the InciDence of POAF

AF after cardiac surgery leads to excess mortality and morbidity. Colchicine was used in several studies to lower the incidence AF but the results were generally disappointing. There was no benefit in reducing AF and there was a high incidence of GI side effects especially diarrhea, often leading to stopping ...

Phase

Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery

Standard Heparin management, based on total body weight, is not well established for obese patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The purpose of this study is to assess the safety and efficacy of using lean body mass (LBM) to determine pump flow rate and/or Heparin dosage in obese ...

Phase N/A

Influence of Elevated Baseline Serum Creatinine and Body Composition on Acute Kidney Injury in Cardiac Surgery

Acute kidney injury (AKI) is an infrequent but major and well - recognized complication of cardiac surgery (1, 2). Its incidence ranges from 1 to 30% (3). Numerous pre-, intra-, and postoperative factors have been associated with the development of AKI after cardiac surgery (3-19). Most commonly used definitions are ...

Phase N/A