Adrenal Cancer Clinical Trials

A listing of Adrenal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 16 clinical trials
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome (AUSC)

Incidental findings of adrenal tumours,"incidentalomas", occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the

  • 30 views
  • 24 Mar, 2022
  • 3 locations
SPI-62 as a Treatment for Hypercortisolism Related to a Benign Adrenal Tumor (ACSPIRE)

This will be a randomized, double-blind study to evaluate the efficacy, safety, and pharmacological effect of SPI-62 in subjects with hypercortisolism related to a benign adrenal tumor.

  • 0 views
  • 13 Oct, 2022
  • 3 locations
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

3CAR is being done to investigate an immunotherapy for patients with solid tumors. It is a Phase I clinical trial evaluating the use of autologous T cells genetically engineered to express B7-H3-CARs for patients ≤ 21 years old, with relapsed/refractory B7-H3+ solid tumors. This study will evaluate the safety and …

measurable disease
cyclophosphamide
serum pregnancy test
administration intravenous
mesna
  • 0 views
  • 04 Oct, 2022
  • 1 location
PET Biodistribution Study of 68Ga-FAPI-46 in Patients With Different Malignancies: An Exploratory Biodistribution Study With Histopathology Validation (FAPI PET RDRC)

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

pet/ct scan
metastasis
dotatate
cancer
bladder tumor
  • 0 views
  • 13 Oct, 2022
  • 1 location
Phase I/II Trial of Anti-CTLA4-NF mAb (BMS-986218) in Combination With Nivolumab and Hypofractionated Stereotactic Radiation Therapy in Patients With Advanced Solid Malignancies

This phase I/II trial studies the side effects of anti-CTLA4-NF monoclonal antibody (mAb) (BMS986218), nivolumab, and stereotactic body radiation therapy in treating patients with solid malignancies that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as anti-CTLA4-NF mAb (BMS-986218) and nivolumab, may help the …

  • 16 views
  • 13 Oct, 2022
  • 1 location
Calcium Channel Blockade in Primary Aldosteronism

Primary aldosteronism is a common cause of hypertension. Recent evidence suggests that many patients with bilateral idiopathic hyperaldosteronism harbor gain-of-function somatic mutations in zona glomerulosa calcium channels that results in aldosterone production. This finding raises the possibility that calcium channel antagonists may be a targeted therapy to reduce aldosterone production …

hyperaldosteronism
hypertension
adrenal venous sampling
renin
amlodipine
  • 0 views
  • 16 Dec, 2021
  • 1 location
Precise Diagnosis, Treatment and Prognostic Evaluation of Complicated Adrenal Tumor Diseases

The adrenal gland is an important organ that produces life hormones. There are many types of adrenal tumors, which tend to occur in young adults and affect the whole body. It has the dual threat

  • 0 views
  • 08 Jan, 2022
  • 1 location
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

Background Endocrine neoplasms (tumors) are among the fastest growing tumors in incidence in the United States. Furthermore, it is often difficult to distinguish between benign or malignant tumors in cancers of the thyroid, parathyroid, adrenal gland, and pancreas. More research is needed to improve detection and treatment options for patients …

parathyroid
cancer
paraganglioma
endocrine cancer
biochemical testing
  • 185 views
  • 23 Oct, 2022
  • 1 location
Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Background The adrenal gland makes the hormone aldosterone. This helps regulate blood pressure. An adrenal gland tumor that makes too much aldosterone can cause

potassium
urine tests
aldosterone
adrenal neoplasm
primary aldosteronism
  • 126 views
  • 07 Oct, 2022
  • 1 location
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

The PIONEER Initiative stands for Precision Insights On N-of-1 Ex vivo Effectiveness Research. The PIONEER Initiative is designed to provide access to functional precision medicine to any cancer patient with any tumor at any medical facility. Tumor tissue is saved at time of biopsy or surgery in multiple formats, including …

precision medicine
cancer
drug screening
  • 21 views
  • 27 Jan, 2021
  • 1 location