Hepatoblastoma Clinical Trials

A listing of Hepatoblastoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 29 clinical trials
A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy

A Phase 3 multi-institutional study for treatment of children with newly diagnosed hepatoblastoma using a modified Paediatric Hepatic International Tumour Trial (PHITT) strategy incorporating a

carboplatin
fluorouracil
cancer
glomerular filtration rate
metastatic disease
  • 0 views
  • 27 Mar, 2021
  • 1 location
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma

carboplatin
fluorouracil
carcinoma
cancer
etoposide
  • 178 views
  • 01 Aug, 2021
  • 138 locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphomas or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

gliomas
absolute neutrophil count
cancer
total body irradiation
stem cell transplantation
  • 997 views
  • 01 Aug, 2021
  • 114 locations
Paediatric Hepatic International Tumour Trial

The PHITT trial is an over-arching study for patients with Hepatoblastoma (HB) and Hepatocellular Carcinoma (HCC). This trial will use a risk-adapted approach to the treatment of children

carboplatin
fluorouracil
sorafenib
carcinoma
gemcitabine
  • 38 views
  • 27 Jan, 2021
  • 2 locations
Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors

This study uses a double autologous peripheral blood stem cell rescue (PBSC) following dose-intensive chemotherapy for the treatment of high-risk pediatric solid tumors.

primitive neuroectodermal tumor
metastasis
soft tissue sarcoma
ewing's sarcoma
solid tumour
  • 76 views
  • 07 Nov, 2020
  • 1 location
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

Investigators are testing new experimental drug combinations such as the combination of vorinostat, vincristine, irinotecan, and temozolomide in the hopes of finding a drug that may be effective against tumors that have come back or that have not responded to standard therapy. The goals of this study are: To find …

biological factors
cancer
stem cell transplantation
platelet transfusion
drug combinations
  • 3 views
  • 24 Jan, 2021
  • 1 location
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

The phase I portion of this study is designed for children or adolescents and young adults (AYA) with a diagnosis of a solid tumor that has recurred (come back after treatment) or is refractory (never completely went away). The trial will test 2 combinations of therapy and participants will be …

  • 0 views
  • 03 Jul, 2021
  • 2 locations
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well palbociclib works in treating patients with Rb positive solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with activating alterations (mutations) in cell cycle genes that have spread to other places in the body and have come back or do not respond to …

cancer
total body irradiation
cancer treatment
stem cell transplantation
platelet transfusion
  • 91 views
  • 01 Aug, 2021
  • 81 locations
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

cancer chemotherapy
viral therapy
biological factors
cytokines
EGFR
  • 293 views
  • 30 Apr, 2021
  • 1 location
Ivosidenib in Treating Patients With Advanced Solid Tumors Lymphoma or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well ivosidenib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have IDH1 genetic alterations (mutations). Ivosidenib may block the growth of cancer cells that have specific genetic changes …

cns involvement
nervous system disorders
cancer
total body irradiation
cancer treatment
  • 37 views
  • 01 Aug, 2021
  • 89 locations