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Stomach Cancer Clinical Trials

A listing of Stomach Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (105) clinical trials

Esophageal Cancer Genetics Studies

The overall goal of this project is to understand the role of genetics in the etiology and prevention of upper gastrointestinal cancer, primarily esophageal cancer, but also cancers of the gastric cardia and body. Esophageal cancer is the fourth most common cause of cancer death in China and the seventh ...

Phase N/A

Early Detection of Esophageal Cancer

Esophageal cancer is a common malignancy with a very poor prognosis. The principal reason for its poor prognosis is that most tumors are asymptomatic and go undetected until they have spread beyond the esophageal wall and are unresectable. Significant reduction in esophageal cancer mortality will require successful strategies to diagnose ...

Phase N/A

S-1 and Irinotecan Combination Chemotherapy for Advanced Gastric Cancer

The primary goal of this phase II trial is to evaluate the response rate of combination chemotherapy with S-1 and Irinotecan in patients with advanced gastric cancer as a first-line therapy.

Phase

Study of Cetuximab Plus P-HDFL for the First-Line Treatment of Advanced Gastric Cancer

Non-resectable gastric cancer is an incurable disease. Systemic chemotherapy confers prolongation of survival and improvement of quality of life. Regimens containing cisplatin and 5-fluorouracil (5-FU) are widely adopted in the world. A P-HDFL regimen, based primarily on weekly 24-hour infusion of cisplatin and high-dose 5-FU and leucovorin, is commonly used ...

Phase

Chemoradiation-Induced Nausea and Emesis: Quality of Life

You will be interviewed about your perceptions of side effects that are related to your chemoradiation treatment. The interview will take about 20 minutes. You will be interviewed at the beginning of your chemoradiation treatment, 3 weeks after treatment starts, and at the first follow-up appointment after chemoradiation treatment ends. ...

Phase N/A

Combination Chemotherapy and Bevacizumab in Treating Patients With Recurrent Unresectable or Metastatic Gastric Cancer Gastroesophageal Junction Cancer or Esophageal Cancer

OBJECTIVES: Primary - Determine the efficacy of combination chemotherapy comprising modified docetaxel, cisplatin, fluorouracil, and leucovorin calcium with bevacizumab, as measured by 6-month progression-free survival (PFS), in patients with locally recurrent, unresectable, or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma. Secondary - Determine the safety of this regimen in these ...

Phase

Perioperative Chemoradiotherapy for Potentially Resectable Gastric Cancer

Rationale: Adjuvant chemoradiation considered as standard of care after curative surgery for adenocarcinoma of stomach and gastroesophageal cancer. Preoperative chemotherapy in the in locally advanced gastric cancer results in significant tumoral downstaging with improved rate of curative resections. Purpose: To evaluate feasibility and safety of combination of preoperative chemotherapy and ...

Phase

Comparison of Laparoscopic Versus Open Gastrectomy for Gastric Cancer: A Prospective Randomized Trial

Recently, in technical aspects, almost all kinds of open gastric cancer surgeries can be reproduced laparoscopically. However, many controversies exist due to no evidence and no long-term results. There was no prospective multi-center large-scale randomized controlled trial in the world on the long-term outcome of laparoscopic gastric cancer surgery. Korean ...

Phase

Biomarkers and Radiation Side Effects in Patients Undergoing Radiation Therapy for Gastrointestinal Cancer

OBJECTIVES: Primary - Determine if tumor-specific DNA mutations and aberrant DNA methylation can be detected in the serum, urine, or stool at the time of diagnosis in patients undergoing radiotherapy for gastrointestinal malignancies. - Determine if changes in mutational status at follow up are associated with disease persistence, recurrence, or ...

Phase N/A

Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis

DISEASE CHARACTERISTICS: - Histologically confirmed peritoneal carcinomatosis with the following histologies: - Primary peritoneal mesothelioma - Adenocarcinoma of gastrointestinal tract origin - Confined to peritoneal cavity - Tumor mass could be debulked to less than 2.5 cm in diameter per tumor deposit - Must not have failed prior intraperitoneal platinum ...

Phase