Wilms' Tumor Clinical Trials

A listing of Wilms' Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 64 clinical trials
Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers

To evaluate the safety and tolerability of galinpepimut-S in combination with pembrolizumab in patients with selected advanced cancers. Patients will be followed long-term for Overall Survival (OS) and safety. The study will enroll approximately 90 patients and maximum study treatment duration is approximately 2.13 years.

measurable disease
carcinoma
blood transfusion
fluoropyrimidine
estrogen
  • 130 views
  • 27 Mar, 2021
  • 19 locations
Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission

The primary aim of this innovative immunotherapeutic study is to determine whether the antileukemic effects seen in our previous phase I/II study can be confirmed in a large cohort of patients and whether dendritic cell vaccination can significantly prevent relapse and increase survival of acute myeloid leukemia (AML) patients by …

venetoclax
blast cells
minimal residual disease
consolidation chemotherapies
cell transplantation
  • 24 views
  • 27 Jan, 2021
  • 9 locations
Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors

This is a first-in-human, Phase 1/2 open-label, multicenter, dose-escalation, safety, PK, and biomarker study of PBI-200 in subjects with NTRK-fusion-positive advanced or metastatic solid tumors.

NTRK
measurable disease
systemic therapy
  • 13 views
  • 09 Sep, 2021
  • 4 locations
GPS Compared With BAT in AML CR2/CR2p

To assess the safety and efficacy of galinpepimut-S compared with investigator's choice of best available therapy (BAT) on overall survival (OS) in subjects with acute myeloid leukemia (AML) who are in second complete remission 2 (CR2)/second complete remission with incomplete platelet recovery (CR2p).

decitabine
venetoclax
blast cells
serum bilirubin level
remission
  • 1 views
  • 24 Jan, 2021
  • 2 locations
COZMOS:Phase I/Ib Trial of Combined 5'Azacitidine and Carboplatin for Recurrent/Refractory Pediatric Brain/Solid Tumors

Many pediatric brain and solid tumors have altered epigenetic landscapes, and altered DNA methylation. As such this study is a Phase I/Ib study of combined 5'Azacitidine with an escalating dose of carboplatin for all recurrent/refractory pediatric brain and solid tumors. The phase I component will establish with maximum tolerated dose …

solid tumor
neutrophil count
myelosuppressive chemotherapy
anticonvulsants
metastatic disease
  • 278 views
  • 28 Aug, 2021
  • 17 locations
Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

This Phase I dose-escalation trial is designed to evaluate the safety of administering rapidly -generated tumor multi-antigen associated -specific cytotoxic T lymphocytes, to HSCT recipients (Arm A) or future HSCT recipients (Arm B) for the treatment of high-risk or relapsed or refractory hematopoietic malignancies. In addition to safety, this study …

  • 19 views
  • 02 Aug, 2021
  • 2 locations
Tumor and Development (TED)

The overall project goal is to build a database of childhood cancers associated with developmental anomalies; it aims at identifying new syndromes of genetic predisposition and at enabling the further study of their molecular basis.

  • 0 views
  • 04 Jul, 2021
  • 2 locations
Therapeutic Recommendations for Nephroblastoma

The study is based on results form 2 previous studies carried out by the GFAOP. The aim of this study is to evaluate the capacity of units to follow the recommendations in the protocol.

  • 0 views
  • 15 Jul, 2021
  • 4 locations
Study of Kidney Tumors in Younger Patients

This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

kidney tumor
metanephric adenoma
ct scan
carcinoma
anaplasia
  • 675 views
  • 28 Aug, 2021
  • 105 locations
International PPB/DICER1 Registry

Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a partially cystic, partially solid tumor, Type III is a completely solid tumor. Treatment of children with PPB is at the discretion of the …

solid tumor
initial diagnosis
cancer
cancer chemotherapy
sarcoma
  • 37 views
  • 08 Aug, 2021
  • 1 location