Wilms' Tumor Clinical Trials

A listing of Wilms' Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 63 clinical trials
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have recurred or spread to other places in the body (advanced), lymphoma, or histiocytic disorders, that have a genetic alteration in the gene HRAS. Tipifarnib may block the growth of cancer cells …

metastasis
pleural effusion
absolute neutrophil count
cns tumor
chemotherapeutic agents
  • 10 views
  • 12 Sep, 2021
  • 88 locations
Hypomemylating Agents Combination With eDC Therapy for Elderly Patients With Myelodysplastic Syndrome

this innovative immunotherapy using WT1/hTERT/Survivin-loaded DCs is to determine whether this novel DC vaccination is safe and can significantly prevent clinical relapse and increase survival of MDS

cell transplantation
  • 0 views
  • 22 Aug, 2021
  • 1 location
Clinical Study of DC-AML Cells in the Treatment of Acute Myeloid Leukemia

The primary aim of this innovative immunotherapy using WT1/hTERT/Survivin-loaded DCs is to determine whether this novel DC vaccination is safe and can significantly prevent clinical relapse and

flow cytometry
blast cells
remission
residual tumor
consolidation chemotherapies
  • 0 views
  • 28 Aug, 2021
  • 1 location
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

metastatic disease
biologic agent
antibody therapy
solid tumour
cytokines
  • 308 views
  • 30 Apr, 2021
  • 1 location
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

The purpose of this study is to determine if Magnetic Resonance guided High Intensity Focused Ultrasound ablative therapy is safe and feasible for children, adolescents, and young adults with refractory or relapsed solid tumors.

tumor liver
solid tumour
hifu
filgrastim
monoclonal antibodies
  • 274 views
  • 07 Aug, 2021
  • 2 locations
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

biologic agent
antibody therapy
solid tumour
cytokines
iobenguane
  • 0 views
  • 27 Apr, 2021
  • 1 location
Ivosidenib in Treating Patients With Advanced Solid Tumors Lymphoma or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well ivosidenib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have IDH1 genetic alterations (mutations). Ivosidenib may block the growth of cancer cells that have specific genetic changes …

metastasis
pleural effusion
chemotherapeutic agents
cns tumor
cytotoxic chemotherapy
  • 37 views
  • 12 Sep, 2021
  • 90 locations
Selpercatinib for the Treatment of Advanced Solid Tumors Lymphomas or Histiocytic Disorders With Activating RET Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well selpercatinib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphomas, or histiocytic disorders that have activating RET gene alterations. Selpercatinib may block the growth of cancer cells that have specific genetic changes …

RET
metastasis
pleural effusion
absolute neutrophil count
cns tumor
  • 18 views
  • 12 Sep, 2021
  • 90 locations
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well vemurafenib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with BRAF V600 mutations that have spread to other places in the body (advanced) and have come back (recurrent) or do not respond to treatment (refractory). Vemurafenib may …

dabrafenib
metastasis
chemotherapeutic agents
cns tumor
cytotoxic chemotherapy
  • 236 views
  • 22 Aug, 2021
  • 76 locations
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well palbociclib works in treating patients with Rb positive solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with activating alterations (mutations) in cell cycle genes that have spread to other places in the body and have come back or do not respond to …

metastasis
pleural effusion
chemotherapeutic agents
cns tumor
cytotoxic chemotherapy
  • 115 views
  • 12 Sep, 2021
  • 81 locations