Oral Cavity Cancer Clinical Trials

A listing of Oral Cavity Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 84 clinical trials
Submandibular Gland Preservation in Neck Dissection

Trial design: a randomized controlled trial. Eligibility criteria for participants: patients with primary early stage oral squamous cell carcinoma. Exclusion criteria: cancer of the floor of the mouth. Interventions: submandibular gland is preserved during neck dissection for patients of the experimental group; submandibular gland is removed during neck dissection for …

carcinoma
neck dissection
squamous cell carcinoma
  • 0 views
  • 23 Jan, 2021
  • 1 location
Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

This phase IV trial studies how well serial magnetic resonance imaging (MRI) after radiation therapy works in predicting radiation-induced changes in the normal tissue of patients with oral cavity or skull base tumors. Performing MRIs after radiation therapy for patients with oral cavity or skull base tumors may help to …

caries
  • 0 views
  • 23 Jan, 2021
  • 1 location
Use of Ultrasound for Measuring Size of Oral Tongue Cancers

The purpose of this study is to investigate the use intraoral ultrasound for measuring depth of invasion (DOI) in oral tongue squamous cell carcinoma. The DOI's measured on ultrasound and measurements from MRI scans, will be compared to the measurements made from pathological examination of removed specimens.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue

prospective clinical trial. Positive outcomes from this study have the potential to dramatically alter the most common morbidity of oral cancer therapy, namely speech and swallowing function in a population

oral cancer
new diagnosis
cancer treatment
  • 21 views
  • 11 Jul, 2021
  • 1 location
MSOT Using Cetuximab-800CW for Detection of Cervical Lymph Node Metastases

The presence of lymph node metastasis is an important factor in determining the appropriate treatment plan in patients with OSCC. However, detection of lymph node metastases by means of current imaging modalities is limited. 20-30% of patients with a clinically negative neck (cN0) harbour lymph node metastasis that were not …

neck tumor
carcinoma
metastasis
sentinel node
squamous cell carcinoma of the head and neck
  • 9 views
  • 10 May, 2021
  • 1 location
Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers

This phase I/II trial studies the side effects and how well nivolumab and ipilimumab works when given together with stereotactic body radiation therapy (SBRT) in treating patients with salivary gland cancers. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and …

carcinoma
neutrophil count
metastasis
platelet count
measurable disease
  • 0 views
  • 28 Jul, 2021
  • 1 location
A Study of APG-115 in Patients With Salivary Gland Carcinoma

This is a phase I/II trial to evaluate the efficacy of APG-115 +/- Carboplatin for the treatment p53 wild-type malignant salivary gland cancer. Part 1 consists of 2 arms, arm A is APG-115 monotherapy and arm B is APG-115 + Carboplatin Part 2 is single arm based on the outcome …

  • 0 views
  • 02 Jun, 2021
  • 2 locations
PSMA-PET Imaging Before and After ADT in Advanced SDC Patients

Explorative study, which evaluates the effect of androgen deprivation therapy (ADT) on the PSMA ligand uptake on 68Ga-PSMA-PET/CT in salivary duct carcinoma patients.

  • 1 views
  • 16 Apr, 2021
  • 1 location
Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

This research is being done to see how safe and effective the use of the study drug Ado-trastuzumab (T) emtansine (DM1), T-DM1, and standard of care chemoradiation are when used together in treating HER2-positive salivary gland cancer. It will also examine the effectiveness of study drug Ado-trastuzumab (T) emtansine (DM1) …

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery

This clinical trial studies wide-field and high resolution in vivo imaging in visualizing lesions in patients with abnormal or uncontrolled oral cell growth (neoplasia) undergoing surgery. Diagnostic procedures, such as wide-field and high resolution in vivo imaging, are devices that let researchers look at a wide area of the lining …

  • 191 views
  • 25 Jul, 2021
  • 1 location