Oral Cavity Cancer Clinical Trials

A listing of Oral Cavity Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 25 clinical trials
Dissecting the Heterogeneity of Oral Cancer Pain

Oral squamous cell carcinoma (SCC) produces a higher prevalence and more severe pain than all other cancers. Orofacial pain is one of the most common initial symptoms of oral cancer and often

Accepts healthy volunteers
  • 17 Oct, 2022
  • 1 location
Pharmacokinetic (PK) Analysis of Antitumor B in Patients With Oral Cancer

A Window of Opportunity Clinical Trial. This study design permits examination of effects of an oral agent on cancer patients during the "window" between diagnosis of their cancer and their definitive cancer surgery. Similar to a phase 0 study, the trial design permits examination of the biologic effects of an …

  • 04 Oct, 2022
  • 1 location
Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial

Project's goal is evaluate an online tool the research team created called Empowered Survivor (ES) against a free online self-management intervention developed for cancer survivors by the National Cancer Institute and the American Cancer Society called Springboard Beyond Cancer.

carcinoma of oropharynx
oral cancer
  • 04 Oct, 2022
  • 1 location
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

oral cavity cancer. Sentinel lymph node biopsy surgery is a procedure that removes a smaller number of lymph nodes from your neck because it uses an imaging agent to see which lymph nodes are most

mouth cancer
ct scan
chest x-ray
step 2
  • 04 Oct, 2022
  • 25 locations
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

solid tumor
systemic therapy
squamous cell carcinoma
  • 04 Oct, 2022
  • 24 locations
Topical Aldara (Imiquimod) for Oral Cancer

The purpose of this research study is to find out what effects, good and/or bad, topical application of the drug Aldara will have on patients and on their oral cancer. Aldara is a drug that

oral cancer
squamous cell carcinoma
tumor cells
  • 07 Oct, 2022
  • 1 location
Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

approved for the treatment of diabetes, but studies have shown that it may have some anticancer properties. Giving metformin may help prevent or slow the development of oral cancer from precancerous

precancerous lesions
  • 07 Oct, 2022
  • 1 location
Radiotherapy of Head and Neck Cancer Using an Intraoral Stent

Radiotherapy of oral cavity cancer and sinonasal cancer is associated with acute and late morbidity. Use of an intraoral stent will provide a larger distance between the tongue and palate and

neck cancer
carcinoma of oral cavity
head and neck cancer
  • 07 Oct, 2022
  • 1 location
Genomic Profiling and Matched Therapy for Recurrent or Metastatic Salivary Gland Neoplasms

This is a study of select drug therapies in patients with salivary gland cancer. The study has two phases: a molecular profiling phase (phase 1) and a treatment phase (phase 2). Based on the Molecular profiling results in phase the participants will receive matched treatment if a specific aberration is …

  • 15 Oct, 2022
  • 1 location
Cyclin D1 Based TPF(Docetaxel, Cisplatin and 5-fluorouracil) Induction Chemotherapy for OSCC(Oral Squamous Cell Carcinoma) Patients at cN2(Clinical Node 2) Stage: a Phase II Randomized Controlled Trial

The purpose of this study is to To confirm the predictive value of CCND1 for TPF induction in cN2 patients with OSCC

squamous cell carcinoma of the oral cavity
external radiation
squamous cell carcinoma
  • 20 Oct, 2022
  • 1 location