Oral Cavity Cancer Clinical Trials

A listing of Oral Cavity Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 84 clinical trials
Oral Cancer Adjuvant Therapy (OCAT) Trial

To demonstrate whether addition of Concurrent chemotherapy to post-operative adjuvant radiotherapy OR shortening of duration of post-operative radiotherapy, by administering 6 fractions / week instead of 5 fractions / week improves local-regional control and / or overall survival in high risk, locally advanced, resectable, squamous cell carcinoma of oral cavity.

chemoradiotherapy
squamous cell carcinoma
caries
adjuvant therapy
carcinoma
  • 60 views
  • 07 Nov, 2020
  • 1 location
Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of the Mouth or Oropharynx

surgery and radiation therapy alone to see how well they work compared to surgery, radiation therapy, and interleukin-2 in treating patients with cancer of the mouth or oropharynx.

immunomodulator
tumor cells
x-rays
oral cancer
interleukin-2
  • 18 views
  • 07 Nov, 2020
  • 1 location
  • 4 views
  • 21 Jan, 2021
  • 2 locations
Free Soft Tissue Graft in Treatment of Oral Lichen Planus

influence the risk for oral cancer. The purpose of the study is to determine the efficacy of free soft tissue graft in the treatment of precancerous and symptomatic lesions of OLP. Removal of

epithelial cells
immunosuppressant
atrophic
oral cancer
ulceration
  • 0 views
  • 07 Nov, 2020
  • 1 location
Immune Checkpoint Inhibitor In High Risk Oral Premalignant Lesions

size or in grade of dysplasia) may not be enough to assess the potential benefit of an intervention. Modulation of molecular markers may be more precise indicator of oral cancer risk in patients with

  • 0 views
  • 27 Jan, 2021
  • 5 locations
Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach

This research protocol is comparing the effectiveness of surgical excision to the "wait and see" approach for the management of oral leukoplakia and erythroleukoplakia in prevention of oral squamous cell carcinoma onset.

  • 0 views
  • 08 May, 2021
  • 1 location
Concomitant Immune Check Point Inhibitor With Radiochemotherapy in Head And Neck Cancer

Background: Locally advanced head and neck cancer (HNC) is a challenge as, in spite of initial good control with chemoradiation, the majority of patients fails systemically. In the last 2 years, immune check points inhibitors (mainly Programmed Death (PD)-1 inhibitors) were approved for metastatic/recurrent HNC. The favorable toxicity profile and …

  • 25 views
  • 26 Apr, 2021
  • 1 location
Hyperbaric Oxygen Treatment of Mandibular Osteoradionecrosis. A Randomized Clinical Study

There is currently not sufficient evidence that hyperbaric oxygen (HBO) benefits the surgical removal of necrotic bone in osteoradionecrosis patients. This study aims at testing the hypothesis that HBO does improve healing after surgical removal of necrotic bone in irradiated previous head and neck cancer patients compared to not receiving …

  • 66 views
  • 07 Nov, 2020
  • 1 location
Androgen Deprivation Therapy in Advanced Salivary Gland Cancer

Salivary Gland (SG) Cancers are a rare and heterogeneous group of tumors, usually approached by multidisciplinary teams in high specialized centers. Until today no standard of care exists to treat these cancers. The identification of a target, the androgen receptor, in SG tumors has allowed for new treatment strategies options …

  • 161 views
  • 25 Jan, 2021
  • 25 locations
Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial

Project's goal is evaluate an online tool the research team created called Empowered Survivor (ES) against a free online self-management intervention developed for cancer survivors by the National Cancer Institute and the American Cancer Society called Springboard Beyond Cancer.

  • 0 views
  • 15 Apr, 2021
  • 1 location