Search Medical Condition
Please enter condition
Please choose location

Oral Cavity Cancer Clinical Trials

A listing of Oral Cavity Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (65) clinical trials

Pembrolizumab in Combination With CRT for LA-SCCHN

Each subject will participate in the trial from the time the subject signs the Informed Consent Form (ICF) through the final protocol-specified contact. After a screening phase of 28 days, eligible subjects will receive treatment on Day -7 with a loading dose of the study drug. This will continue during ...

Phase

Validation of DNA Methylation Biomarkers for Oral Cancer Detection

In this study, investigators plan to recruit 40~50 patients who had, or currently has oral cancer. The study procedures are as below: - After the Informed Consent Form is signed, swab from the lesion site and normal site to obtain oral epithelial cells. - Collect tissue from the tumor site ...

Phase N/A

Window Study of Nivolumab With or Without Ipilimumab in Squamous Cell Carcinoma of the Oral Cavity

This research study is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of an investigational intervention to learn whether the intervention works in treating a specific disease. "Investigational" means that the intervention is being studied. The purpose of this study is to evaluate effectiveness ...

Phase

Patient Evaluation for Head and Neck Surgery Branch Studies

This protocol will provide a means for screening potential candidates for head and neck surgery branch protocols. No investigational treatments will be administered in this protocol. The PI may, however, approve a patient who has been determined to be ineligible for HNSB protocols to undergo standard treatment because they present ...

Phase N/A

NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Patients With Locally Advanced Squamous Cell Carcinoma of the Oral Cavity or Oropharynx

Patients will receive a single administration of NBTXR3 on day 1, either as an intra-arterial or intratumor injection, followed by Intensity Modulated Radiation Therapy starting 24 hours later (day 2), and up to completion of 7 weeks, i.e. 70 Grays, 2Grays/fraction. Patients whose tumor has completely shrunk will be followed ...

Phase

Least Invasive Nonlinear Light Microscopy

Evaluate the ability to image oral mucosa in healthy volunteer by nonlinear microscopy

Phase N/A

Trial of IIb Preserving Neck Dissection

Surgery of the cervical lymphatic system has evolved a lot since the introduction of classical radical neck dissection by Crile in 1906, which was later established by Martin (1945). It includes the removal of cervical lymphatic levels I-V along with removal of non-lymphatic structures namely submandibular gland, tail of parotid, ...

Phase

Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer

PRIMARY OBJECTIVES: I. To evaluate the predictive value of the circulating tumor DNA for disease-free survival/progression-free survival in patients with advanced head and neck carcinoma (HNC) and non-small cell lung cancer (NSCLC). SECONDARY OBJECTIVES: I. To correlate the levels of plasma tumor DNA with the salivary tumor DNA. II. To ...

Phase N/A

Maintenance Tegafur-uracil in Resected Oral Cavity Cancer With ECS+

The primary endpoint will be 2-years distant failure rate which will be estimated by Kaplan-Meier method with two-sided 95% confidence interval. The secondary endpoints are described as follows: 2-year locoregional failure rate, 2-year PFS rate and 2-year OS rate will be estimated by Kaplan-Meier method with two-sided 95% confidence interval. ...

Phase

Early Non Invasive Ventilation and Hematological Malignancies

Study Groups: If you agree to take part in this study, you will be randomly assigned (as in the flip of a coin) to 1 of 2 groups. This is done because no one knows if one study group is better, the same, or worse than the other group. You ...

Phase N/A