Mastectomy Clinical Trials

A listing of Mastectomy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 44 clinical trials
Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy

This phase III trial studies how well Mepitel Film works in reducing radiation dermatitis (redness and peeling) in patients with breast cancer during radiation therapy after a mastectomy

endocrine therapy
inflammatory breast cancer
erbb2
mastectomy
HER2
  • 0 views
  • 04 Oct, 2022
  • 11 locations
Serratus Anterior Plane Block to Prevent Chronic Pain in Breast Cancer Surgery: A Randomized Controlled Trial (USB22)

preoperatively after a modified radical mastectomy makes it possible to reduce the intensity and incidence of chronic post-surgical pain in breast cancer.

cancer
postoperative pain
mastectomy
lidocaine
  • 0 views
  • 10 Oct, 2022
  • 1 location
Real-time Intraoperative Breast Cancer Visualization for Margin Assessment

breast cancer patients. Phase 2: to determine the ability of this novel fluorescence imaging agent to predict the presence of positive margins around partial mastectomy specimens and positive

lumpectomy
mastectomy
  • 0 views
  • 07 Oct, 2022
  • 1 location
Accelerated Radiation Therapy (ART) To The Breast And Nodal Stations After Neo-Adjuvant Systemic Therapy And Surgery: A Feasibility Study (ART)

This protocol is for patients with newly diagnosed breast cancer with an indication for post-operative radiotherapy after neo-adjuvant chemotherapy and surgery.

sentinel node
breast surgery
mastectomy
immunostimulant
adjuvant chemotherapy
  • 10 views
  • 25 Oct, 2022
  • 3 locations
Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer

This phase I trial tests the side effects and best dose of abemaciclib and niraparib in treating patients with breast cancer that is positive for estrogen or progesterone receptors (hormone receptor positive [HR+]) and HER2 negative. Abemaciclib may stop the growth of tumor cells by blocking certain proteins called cyclin-dependent …

  • 0 views
  • 04 Oct, 2022
  • 1 location
The Safety and Effectiveness of DuraSorb® for Reinforcement in Patients Undergoing Prosthetic Breast Reconstruction

This study compares outcomes of prospective mesh-based breast reconstructions to historical control breast reconstructions with no mesh.

  • 42 views
  • 13 Oct, 2022
  • 4 locations
A Single Arm Phase 2 Study of Peri-Operative Ipilimumab, Nivolumab and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer.

The purpose of this study is to determine the impact of pre-operative cryoablation, ipilimumab and nivolumab on on 3-year Event Free Survival (EFS), in women with residual hormone receptor negative, HER2-negative ("triple negative") resectable breast cancer after taxane-based neoadjuvant chemotherapy.

erbb2
breast surgery
mastectomy
HER2
invasive carcinoma
  • 0 views
  • 28 Oct, 2022
  • 3 locations
Evaluation of Oxygen Delivery With TransCu O2 to Study Success Rate of Surgically Closed Wounds

This is an exploratory randomized controlled trial study to test feasibility, acceptability, and proof of concept efficacy of Continuous Diffusion of Oxygen (CDO) adjunct therapy for decreasing healing time and reducing tissue necrosis post breast reconstruction. The investigator will assess the benefit of this novel adjunct therapy on successful closure, …

wound treatment
  • 0 views
  • 23 Oct, 2022
  • 1 location
Partial Irradiation and Sequential vs. Concurrent Chemo Early Breast Cancer

In a small study at Johns Hopkins, women were treated with partial breast irradiation and chemotherapy given at the same time. We are now testing in a bigger study whether giving partial breast irradiation and chemotherapy at the same time (our new method) has the same side effects and outcomes …

endocrine therapy
primary tumor
carboplatin
doxorubicin
partial breast irradiation
  • 32 views
  • 07 Oct, 2022
  • 6 locations
Evaluating the Use of Enhanced Recovery Strategies and Paravertebral Block in Elective Breast Reduction and Breast Augmentation

Postoperative pain, nausea, and vomiting are frustrating sequelae of elective breast surgery. Poorly managed postoperative pain can lead to increased opioid use, increased postoperative nausea and vomiting (PONV), delayed return to work and usual activities, unplanned hospital admissions, surgical complications, and patient dissatisfaction. In light of the growing opioid epidemic …

analgesics
elective surgery
breast surgery
local anesthesia
vomiting
  • 162 views
  • 22 Oct, 2022
  • 1 location