Mastectomy Clinical Trials

A listing of Mastectomy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 47 clinical trials
Trial Evaluating Role of Post Mastectomy Radiotherapy in Women With Node Negative Early Breast Cancer (PMRT-NNBC)

patterns of failure for post-mastectomy patients treated without radiation. Many of these series have analyzed several high risk factors which were predictive of loco-regional recurrence wherein the role

  • 31 views
  • 04 Oct, 2022
  • 2 locations
Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain (KALPAS)

The study utilizes a 3-arm placebo-controlled RCT to study the effectiveness of ketamine in reducing chronic post-mastectomy pain. Participants randomized to the first arm will receive a 0.35 mg

  • 0 views
  • 23 Oct, 2022
  • 5 locations
Open Label Case Reports Investigating Wound Healing, Aesthetic Outcomes, and Patient Satisfaction Following Nipple-Areolar Complex (NAC) Reconstruction Using a Decellularized Donor NAC Graft (DCLNAC)

To evaluate the wound healing response following nipple-areolar complex (NAC) reconstruction with a decellularized donor NAC graft (DCLNAC)

  • 0 views
  • 25 Oct, 2022
External Vacuum Expansion: Evaluation in Breast Reconstructive Surgery Evaluation in Breast Reconstructive Surgery

mastectomy (or having undergone mastectomy in the past) will be randomized to undergo breast reconstruction with either AFT with the EVEBRA device(intervention group) or AFT without the EVEBRA device

  • 21 views
  • 04 Oct, 2022
  • 3 locations
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial (LOLIPOP)

The LOLIPOP Trial is a large (n=4,300 patients) pragmatic, international, multicentre, prospective, randomised, double blind, placebo-controlled, parallel assessment, safety and effectiveness superiority study.

breast cancer
mastectomy
breast-conserving surgery
cancer
  • 0 views
  • 07 Oct, 2022
  • 1 location
Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast (ROMANCE)

Following breast-conserving surgery (BCS) for localized ductal carcinoma in situ (DCIS) of the breast, whole-breast irradiation (WBRT) is a standard of care, reducing the absolute rate of in-breast recurrences (IBR) by more than 15% at 10 years, from 28% without radiotherapy to 13 % with radiotherapy. Half of the recurrences …

carcinoma
cish
epidermal growth factor
growth factor
re-excision
  • 52 views
  • 04 Oct, 2022
  • 28 locations
Randomized Trial of Hypofractionated LocoRegional Radiotherapy in Breast Cancer and Lymphedema (RHEAL) (RHEAL)

breast conserving surgery (BCS), or to the chest wall and regional nodes following mastectomy, is non-inferior to conventional fractionation delivered over 3 weeks in patients with node positive breast

carcinoma
breast-conserving surgery
cancer
invasive carcinoma
mastectomy
  • 0 views
  • 24 Oct, 2022
  • 15 locations
De-Escalation of Adjuvant Chemotherapy in HER2-positive, Estrogen Receptor-negative, Node-negative Early Breast Cancer Patients Who Achieved Pathological Complete Response After Neoadjuvant Chemotherapy and Dual HER2 Blockade (Decrescendo)

radiotherapy will be mandatory after breast-conserving surgery, whereas it will be performed according to local guidelines after mastectomy, and it will be administered concomitantly with pertuzumab and

  • 0 views
  • 22 Oct, 2022
  • 39 locations
The Postoperative Radiotherapy in N1 Breast Cancer Patients (PORT-N1)

This study is a multicenter, randomized, phase 3 clinical trial in patients with breast cancer, randomizing radiotherapy group (postmastectomy radiation therapy (PMRT)/whole breast irradiation plus regional radiotherapy (WBI+regional RT) versus and no PMRT/WBI alone group. This is a non-inferiority study aiming that there is no significant difference in the 7-year …

epidermal growth factor
growth factor
hormone therapy
mastectomy
EGFR
  • 0 views
  • 07 Oct, 2022
  • 1 location
A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.

  • 0 views
  • 21 Oct, 2022
  • 424 locations