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Endometrial Cancer Clinical Trials

A listing of Endometrial Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (46) clinical trials

The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)

If you agree to take part in this study, you will have a single sample (8-10 teaspoons) of blood collected, depending upon current health status. The blood will be drawn at MD Anderson. If you cannot come to the clinic, a blood drawing kit will be sent to the your ...

Phase N/A

Molecular Markers in Treatment in Endometrial Cancer

This is a prospective multicenter study to investigate the predictive value of molecular markers in endometrial cancer for lymph node metastasis, prognosis and treatment. For the previously studied tumor markers p53, p16, ER, PR and HER2neu, we want to investigate the expression in curettage material in relation to lymph node ...

Phase N/A

Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia Oxford Trent or West Midlands Regions of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of endometrial cancer cases. - To define the proportion of endometrial cancer incidence attributable to mutations in known predisposing genes such as MSH2 and MLH1. - To determine the risk associated with these predisposing mutations by examining ...

Phase N/A

Collecting Endometrial and Ovarian Tissues Samples From Patients Without Cancer Undergoing a Hysterectomy

OBJECTIVES: - Collect blood and tissue samples from patients undergoing hysterectomy for a non-cancerous condition to help doctor identify markers that would indicate increased risk for developing endometrial cancer. OUTLINE: This is a pilot study. Patients complete questionnaires including information on race and ethnic background, education, marital status, family history, ...

Phase N/A

Questionnaire Study for Gynecological Cancer Survivors

Since the early 1970s, death rates for the major gynecological tumors have significantly declined, with a reduction of 42% for endometrial, 49% for cervix, 27% for vagina and vulva, and 11% for ovarian cancer. Thus, of the approximately 82,000 new gynecologic cases each year, more women will be living and, ...

Phase N/A

Tissue Bank of Biological Specimens From Patients With Gynecologic Disease

Cancer arises due to genetic alterations that disrupt numerous cellular functions including proliferation, programmed cell death and senescence, that ultimately control the number of cells in a population. The genetic damage that underlies the development of cancers has a diverse etiology and loss of DNA repair mechanisms also may play ...

Phase N/A

Cytokine Regulation of Natural Killer Receptors in Inhibiting Activated T Cell Function

In our extended studies, we have directly examined the expressions of various inhibitory natural killer cell Receptors (iNKRs) on Tumor-infiltrating lymphocytes (TILs) derived from human Cervical cancer (CC) by triple-color flow cytometry with combination of different surface markers. We found up-regulated expression of certain iNKRs (CD94/NKG2A) in TILs and in ...

Phase N/A

The Role of Functional MRI and Doppler Sonography in Assessing Blood Vessel Formation Within the Tumors of Endometrial Cancer Patients

Adenocarcinoma of the endometrium is the fourth most frequent cancer in women. Surgery is the treatment of choice in patients with noninvasive or locally advanced disease. The surgical technique consists of an exploratory laparotomy, with total hysterectomy, bilateral oophorectomy, peritoneal washing, and, in selected high-risk patients, omental and peritoneal biopsies ...

Phase N/A

Familial Colorectal Cancer Registry in Hispanics

Data obtained from this study will serve as the foundation for our large, island-wide, population-based, genetic-epidemiologic study of familial colorectal cancer in Puerto Rico. Through this feasibility study, we will assess the feasibility: (1) of recruiting colorectal cancer patients using the PR Central Cancer Registry, (2) of evaluating family pedigrees ...

Phase N/A