Endometrial Cancer Clinical Trials

A listing of Endometrial Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 93 clinical trials
Featured trial
Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy. (POD1UM-204)

This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial cancer that has progressed on or after

metastatic endometrial cancer
platinum-based chemotherapy
cancer
  • 8 views
  • 02 Jul, 2022
  • 51 locations
Featured trial
A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of INCMGA00012 (formerly MGA012) in Patients with Advanced Solid Tumors

500 mg every 4 weeks in patients with endometrial cancer, specifically either microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR). Additionally, every 3 week (Q3W) flat-dosing

primary cancer
endometrial carcinoma
measurable disease
cancer
  • 295 views
  • 10 May, 2022
  • 17 locations
Featured trial
A Phase 1 Open-Label, Dose-Escalation, Safety and Tolerability Study of INCAGN02385 in Participants With Select Advanced Malignancies

The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies.  This investigational intervention treatment uses a single biological drug and is conducted in two parts. Part 1: INCAGN02385 at the protocol-defined starting dose administered every 2 weeks (Q2W), with dose …

ovarian cancer
urothelial carcinoma
metastatic cervical cancer
carcinoma
  • 380 views
  • 10 May, 2022
  • 4 locations
MPA Versus Dydrogesterone for Management of Endometrial Hyperplasia Without Atypia

To compare the efficacy of Medroxyprogesterone Acetate with dydrogesterone in patients having endometrial hyperplasia (EH) without atypia.

  • 0 views
  • 20 Jun, 2022
  • 1 location
Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer

acetate (MA/MPA) alone as fertility-sparing treatment for patients with early endometrial carcinoma.

Accepts healthy volunteers
  • 0 views
  • 27 Apr, 2022
  • 1 location
Study of Envafolimab Alone or With Lenvatinib in Patients With Advanced Endometrial Cancer

This is an open-label, multi-center, multi-corhort Phase II study of Envafolimab alone or with Lenvatinib in patients with advanced endometrial cancer.The primary objective is to evaluate objective response rate of envafolimab alone or with lenvatinib.

  • 0 views
  • 30 Jun, 2022
  • 13 locations
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

increased risk for infertility, metabolic syndrome, and type 2 diabetes mellitus, and possibly for cardiovascular disease and endometrial carcinoma. Polycystic ovary syndrome is diagnosed in adolescents

metformin
letrozole
clomiphene
polycystic ovary syndrome
endometrial carcinoma
  • 244 views
  • 26 May, 2022
  • 1 location
Endometrial Cancer Lymphadenectomy Trial (ECLAT)

endometrial cancer (EC) FIGO Stages I or II and high risk of recurrence. Secondary aims will be to evaluate the effect of LNE on disease free survival (DFS) and quality of life, as well as the complications

  • 30 views
  • 29 Apr, 2022
  • 48 locations
PROfiling Based Endometrial Cancer Adjuvant Therapy (PROBEAT)

This is a prospective, multicenter, randomized phase III trial among women with endometrioid adenocarcinoma with high-intermediate and intermediate risk features to investigate the role of integrated genomic-pathologic classification to determine if participants should receive no adjuvant therapy, vaginal brachytherapy, external beam radiotherapy or chemo-radiation therapy based on molecular features as …

  • 0 views
  • 10 May, 2022
  • 1 location
A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer (EMBER)

cancer or endometrial cancer.

endocrine therapy
erbb2
her2/neu-negative breast cancer
taxane
HER2
  • 230 views
  • 28 Jun, 2022
  • 76 locations