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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (119) clinical trials

This clinical study is researching a new medication to reduce pain in patients who are having a total knee replacement. The medication is provided intravenously prior to surgery. The study is researching the safety and effectiveness of the medication as well as if it will help reduce the amount of ...

Phase

Understanding GMK Sphere Implant Tibiofemoral Kinematics by Means of Dynamic Videofluoroscopy

The objective of this research project is to perform a comparative study on the in vivo kinematics of the GMK Sphere prosthesis in comparison to the conventional GMK PS Fixed Bearing TKA and the GMK UC Fixed Bearing TKA.

Phase N/A

Post-market Registry Study on the Physica System Total Knee Replacement

This is a post-market registry study; the study device is FDA cleared and used according to the intended use. This is a multi-centre, prospective, non-randomized study. Subjects will be implanted with one of the following configurations of the Physica system: Physica KR (Kinematic Retaining), Physica CR (Cruciate Retaining) or Physica ...

Phase N/A

Audiovisual Distraction for Patients Undergoing Total Knee or Hip Replacement Surgery

The perioperative period is often anxiety-provoking experience for many of our patients. Pain and awareness are the two primary concerns voiced most frequently. For total knee and hip replacement surgery, we offer our patients a spinal anesthetic which produces complete sensory blockade below the level of the waist. Despite a ...

Phase N/A

Lymphodreinage Integrated With Kinesio Tape in TKA Patients

Background In the days following knee arthroplasty, the presence of a strong local inflammatory component is associated with pain and functional limitation, which usually resolves within a few months; however, sometimes it can take longer, and sometimes result in a condition of chronic inflammation, albeit modest, that lasts for years. ...

Phase N/A

Effect of Suction Drains in Total Knee Arthroplasty With Tranexamic Acid

Problem Suction drains during TKA present certain costs to the health system and requires additional nursing care. There is no clear evidence that supports their use, and no studies so far have compared blood loss in patients with or without drains when TA is administered during TKA. Hypothesis During total ...

Phase N/A

Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement

PEPPER is a large pragmatic clinical trial to inform patient choice and balance risk tolerances of individuals who face decisions about different drugs and strategies for deep vein thrombosis (DVT) and pulmonary embolism (PE) prevention after total hip (THA) and knee (TKA) replacement. Indeed, clinical equipoise exists to ethically support ...

Phase

Ten Year Implant Survivorship of the ANTHEM Total Knee System

The ANTHEM Study is a prospective, multicentre, cohort study to collect relevant patient reported, clinical, surgical and radiological data from 196 subjects implanted with the ANTHEM Knee System for degenerative joint disease in up to 6 clinical sites globally. Total study duration for study participants will be 10 years with ...

Phase N/A

Movement Pattern Biofeedback Training After Total Knee Arthroplasty

Currently in the United States, more than 700,000 total knee arthroplasty (TKA) surgeries are performed annually, with projections of 3.5 million performed annually by 2030. The increasing incidence of TKA comes with an immediate need for establishing optimal rehabilitation guidelines to remediate common post-TKA physical impairments and improve functional outcomes. ...

Phase N/A

Virtual Reality Rehabilitation in Patients With Total Knee Replacement

In this randomized controlled trial (RCT), the randomization of the sample will be performed by a local software and in a single blind design. Forty patients will be enrolled and after giving the informed consent, assigned to two groups : the experimental group (VRG), which will be undergone to treatment ...

Phase N/A