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Polycystic Ovarian Syndrome Clinical Trials

A listing of Polycystic Ovarian Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (116) clinical trials

Liraglutide 3mg (Saxenda) on Weight Body Composition Hormonal and Metabolic Parameters in Obese Women With PCOS

The drug, liraglutide 3.0 mg was approved for chronic weight management in management in obese adults with an initial BMI of 30 kg/m2 or greater or in overweight adults BMI of 27 kg/m2 or greater with at least one weight-related co-morbid condition as an adjunct to a reduced-calorie diet and ...

Phase

Effects of IL-1 Receptor Antagonism on Testosterone Production in Women With Polycystic Ovary Syndrome

A prospective, interventional, open-label, single-arm, proof-of-concept study: 32 women with Polycystic Ovary Syndrome (PCOS) will be treated with 100 mg of Anakinra/Kineret for 4 weeks. 1 week after last injection patients will have a follow-up and a dexamethasone visit after a dexamethasone suppression test. Goal of this study is to ...

Phase

Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women

Under-carboxylated osteocalcin (ucOC), the precursor substrate of bone biomarker OC is a potent regulator of energy metabolism by promoting insulin production and adiponectin synthesis and decreasing fat stores.UcOC has a potential role in the physiopathology of polycystic ovary syndrome (PCOS), a common disorder defined by the constellation of anovulation, insulinresistance, ...

Phase

Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia

To date, the mechanisms underlying excess androgen production from steroid producing tissues have been unclear, but recent Genome Wide Association Studies (GWAS) have provided additional data in this regard. Initial GWAS data in a Han Chinese population identified some 12 loci as potential PCOS susceptibility gene candidates. One of these ...

Phase N/A

Taichi for Overweight/Obese Adolescent and Young Women With Polycystic Ovary Syndrome (PCOS)

The present study is a randomized pilot study, overweight/obese adolescent and young PCOS subjects will be assigned into two groups: Taichi arm and control arm. Hormonal profile and metabolic profile will be determined.

Phase N/A

Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study

According to preliminary survey, the prevalence of polycystic ovary syndrome (PCOS) among Chinese women reached 7.5%. Hyperandrogenism and insulin resistance were considered as the main pathogenesis of PCOS. As reported, the secretion of androgen is higher among women with PCOS than the healthy reference population throughout their fertile lives. Worth ...

Phase N/A

Functional Study of the Hypothalamus in Magnetic Resonance Imaging (MRI) in Polycystic Ovary Syndrome (PCOS)

The aim to evaluate whether activation of the hypothalamic-pituitary-gonadal axis in PCOS is associated with transient microstructural and metabolic changes in the female hypothalamus using MRI approaches to assess water diffusion and measure proton magnetic resonance spectra.

Phase N/A

Optimisation of Follicular Recruitment in IVM Cycles

The study will focus on important aspects related to follicle recruitment using exogenous gonadotropins in patients with polycystic ovaries: Early follicle recruitment in patients with polycystic ovaries using corifollitropin alfa: does administration of this drug result in earlier and higher FSH (follicle stimulating hormone) concentrations above the threshold for follicle ...

Phase

Ovarian Ultrasonography for the Clinical Evaluation of Polycystic Ovary Syndrome

The purpose of this study is to develop ultrasound criteria for polycystic ovaries for women with PCOS across early, mid and late adulthood and to assess the impact of body composition on these ultrasound criteria.. The study will also compare ultrasound features of the ovary against or in combination with ...

Phase N/A

Adding Prednisolone During Ovulation Induction With CC in Lean Women With CC Resistant PCOS

Women will be randomly divided into two groups; CC-Prednisolone group and CC group. Women in the CC-Prednisolone group will receive CC (150 mg/day for 5 consecutive days from day 2 of cycle) and prednisolone (5 mg/day for 10 consecutive days from day 2 of cycle). Women in the CC group ...

Phase