Colon Cancer Clinical Trials

A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 764 clinical trials
IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting (IROCAS)

, folinic acid, 5-FU (mFOLFOX 6) chemotherapy protocols in patients with high-risk stage III colon cancer in the adjuvant setting.

  • 116 views
  • 04 Oct, 2022
  • 8 locations
D2 vs D3 Lymph Node Dissection for Left Colon Cancer

The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node

adenocarcinoma
  • 0 views
  • 06 Oct, 2021
  • 1 location
Acute Diverticulitis and Advanced Colonic Neoplasia. When to Perform Colonoscopy (ADACOLON Study) (ADACOLON)

This study evaluate the prevalence of advanced colonic neoplasia (ACN) in acute diverticulitis. A sub-analysis of complicated and uncomplicated acute diverticulitis will be made in order to determinate whether there are differences of advanced colonic neoplasia (ANC) prevalence in both groups and to assess if a colonoscopy is necessary.

blood test
computed tomography
  • 2 views
  • 01 May, 2022
  • 1 location
Open Versus Laparoscopic Complete Mesocolic Excision for Locally Advanced Colon Cancer (OLCMECC)

Randomized, multicenter, phase III trial to compare the short and long outcomes of laparoscopic CME with open CME in treating patients with locally advanced colon cancer.

open surgery
metastasis
adenocarcinoma
laparoscopic surgery
  • 3 views
  • 23 Feb, 2022
  • 1 location
Neoadjuvant Chemotherapy for Non-metastatic Locally Advanced Colon Cancer: A Prospective Multicenter Randomized Controlled Trial

The main cause of recurrence after surgical treatment of colon cancer is distant metastasis. Neoadjuvant chemotherapy has potential benefits of improving the effectiveness of chemotherapy

metastasis
adenocarcinoma
adenocarcinoma of colon
folfox regimen
platelet count
  • 1 views
  • 22 Sep, 2022
  • 4 locations
Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial

Comparing the complete resection rate and subsequent adenoma recurrence rate at surveillance colonoscopy of 15-40mm laterally spreading adenomas for conventional EMR vs. cold snare EMR.

adenoma
endoscopic mucosal resection
cold
  • 0 views
  • 18 Feb, 2022
  • 1 location
Circulating Tumor DNA Guided Adjuvant Chemotherapy for Colon Cancer: A Prospective, Multicenter, Open-label, Randomized Controlled Clinical Trial (CTAC)

The IDEA study classified stage III colon cancer into low-risk (T1-3/N1) and high-risk patients (T4 or N2) according to TNM stage. The results showed that for some low-risk patients

  • 0 views
  • 16 Sep, 2022
  • 1 location
Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesia (CAN)

The purpose of this study is to determine whether anesthesia maintained with propofol results in better one- and five-year-survival than anesthesia maintained with sevoflurane.

anesthesia
immunostimulant
propofol
general anesthesia
cancer surgery
  • 30 views
  • 05 Jun, 2022
  • 14 locations
A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001)

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity of selpercatinib (also known as LOXO-292) administered orally to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer (MTC) and other tumors with RET activation.

measurable disease
RET
solid tumour
cfdna
renal function
  • 1279 views
  • 04 Oct, 2022
  • 86 locations
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial

VAPOR-C is a randomised study of the impact of IV versus inhaled anaesthesia (propofol versus sevoflurane) and lidocaine versus no lidocaine on duration of disease free survival inpatients with either colorectal or non small cell lung cancer.

lung carcinoma
  • 0 views
  • 16 Sep, 2022
  • 20 locations