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Cancer Pain Clinical Trials

A listing of Cancer Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (120) clinical trials

Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation

OBJECTIVES: - Compare the incidence and severity of oral mucositis in children undergoing NASA-developed light-emitting diode (LED) therapy during a pre-transplantation myeloablative conditioning regimen (chemotherapy with or without radiotherapy) and continuing through the post-bone marrow transplantation (BMT) phase versus LED therapy during the post-BMT phase only. OUTLINE: This is a ...

Phase

Exercise Program or Health Education Program in Reducing Fatigue and Pain in Breast Cancer Survivors

OBJECTIVES: - Determine whether a moderate-intensity exercise program comprising cardiorespiratory and resistance training of the legs, back, abdominal, trunk, and arm musculature vs a control group attenuates fatigue and pain in breast cancer survivors. - Determine whether this exercise program will significantly improve the quality of life of these patients. ...

Phase N/A

Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

OBJECTIVES: Primary - Compare the frequency and timing of serious related events (e.g., fractures, radiotherapy to bone, hypercalcemia of malignancy, orthopedic surgery, and spinal cord compression) in patients with advanced breast cancer metastatic to the bone treated with bone marker-directed schedule vs standard schedule zoledronic acid. Secondary - Compare the ...

Phase N/A

Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer

OBJECTIVES: Primary - Measure the efficacy of morphine sulfate at 8 weeks after radiofrequency ablation (RFA) of bone metastases. Secondary - Assess minimum and average pain and analyze use of morphine sulfate before and after RFA. - Determine disease progression by CT scan of bone. - Evaluate the percentage of ...

Phase

A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone

This project will enroll 12 volunteers who suffer from chronic pain. Potential participants must be on one of the following therapies: - Long acting morphine - Oxycodone Participants will be asked to complete a pain diary for approximately 10 days and to stop taking their current pain medications the night ...

Phase N/A

Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion

OBJECTIVES: Primary - To evaluate the efficacy of a non-steroidal based regimen comprising ibuprofen in decreasing post-pleurodesis pain as compared to an opiate-based regimen comprising morphine sulfate in patients with malignant pleural effusion. - To evaluate whether chest drain size influences the amount of post-pleurodesis pain. OUTLINE: This is a ...

Phase

Acupuncture in Reducing Ileus in Patients Who Have Undergone Surgery for Colorectal Cancer

OBJECTIVES: Primary - Determine whether a phase III study of acupuncture for postoperative recovery after colorectal surgery is warranted, as defined by evidence of reduction of postoperative ileus in patients who undergo acupuncture vs sham acupuncture after segmental or subtotal colectomy with primary anastomosis for colorectal cancer. Secondary - Determine ...

Phase

Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer

Rationale: Often, incurable cancer patients suffer from severe symptoms as (neuropathic) pain and fatigue with polypharmaceutic interventions as a consequence. Regarding neuropathic pain in incurable cancer patients, pregabalin has been registered for neuropathic non-cancer pain, and amitriptyline is not registered for neuropathic pain, but is recommended as the drug of ...

Phase

Safety of Fentanyl TAIFUN Treatment

A Multicenter, Multinational, Randomized, Open-Label, Parallel-Group Trial to Evaluate hte Safety of Fentanyl TAIFUN Treatment after titrated Dose Administration and the Current Breakthrough Pain Treatment for Breakthrough Pain in Cancer Patients on Maintenance Opioid Therapy

Phase

Peri-Operative Management of Patients Undergoing Laparoscopic Colorectal Surgery

Patients will be randomized into one of 3 groups - A, B or C. In order to remove the major confounding factor of hypovolaemia, all patients will have an oesophageal doppler inserted in order to achieve fluid optimisation. Each group will then either have an epidural, spinal or a PCA ...

Phase