Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 463 clinical trials
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Study Evaluating Safety Tolerability and PK of AMG 757 in Adults With Small Cell Lung Cancer

A study to assess the safety, tolerability, and pharmacokinetics of AMG 757 in Subjects with Small Cell Lung Cancer

delta-like protein 3
cancer chemotherapy
metastasis
platinum-based chemotherapy
pembrolizumab
  • 398 views
  • 17 Nov, 2021
  • 65 locations
None
A Phase 1/2a Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer

CLN-081-101 is a Phase 1/2a, open label, multi-center study of CLN-081 in patients with NSCLC (non small cell lung cancer) harboring EGFR (epidermal growth factor receptor) exon 20 insertion

EGFR
epidermal growth factor
neutrophil count
growth factor
stage iv non-small cell lung cancer
  • 41 views
  • 25 Nov, 2021
  • 19 locations
None
Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)

-resistant small-cell lung cancer (SCLC). This study will be conducted in two parts: safety run-in part and main part. The safety run-in part will be conducted in Japan.

topotecan
carboplatin
measurable disease
  • 0 views
  • 28 Nov, 2021
  • 41 locations
None
DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer

This two-part study will include a dose escalation part to determine the recommended dose for expansion of DS8201a and pembrolizumab and a dose expansion part to evaluate efficacy, safety, and tolerability of the combination.

epidermal growth factor
immunohistochemistry
endocrine therapy
erbb2
stage iv non-small cell lung cancer
  • 0 views
  • 19 Nov, 2021
  • 21 locations
None
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that

alopecia
hysterectomy
monoclonal antibody therapy
durvalumab
platelet count
  • 141 views
  • 01 Dec, 2021
  • 593 locations
None
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. Immunotherapy with

hysterectomy
hepatitis b
tyrosine
tumor cells
hepatitis c virus
  • 231 views
  • 01 Dec, 2021
  • 835 locations
None
Testing the Addition of a New Immunotherapy Drug Atezolizumab (MPDL3280A) to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

This phase II/III trial studies how well chemotherapy and radiation therapy (chemoradiation) with or without atezolizumab works in treating patients with limited stage small cell lung cancer

  • 85 views
  • 01 Dec, 2021
  • 360 locations
None
Screen to Save 2: Rural Cancer Screening Educational Intervention

The purpose of this study is to help the Dartmouth-Hitchcock Norris Cotton Cancer Center and the National Cancer Institute understand how to educate people about cancer screening.

cancer
lung cancer
educational intervention
lung cancer screening
cancer screening
  • 0 views
  • 01 Dec, 2021
  • 1 location
None
Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)

This is a study of the efficacy, pharmacokinetics, and safety of DS-1062a in participants with advanced or metastatic non-small cell lung cancer (NSCLC) with known actionable genomic alterations

kinase inhibitor
tyrosine
NTRK
lung carcinoma
platinum-based chemotherapy
  • 0 views
  • 01 Dec, 2021
  • 89 locations
None
A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer

-positive non-squamous non-small cell lung cancer (NSCLC) that has spread to other parts of the body. Participants who are assigned to the standard treatment and discontinue due to progressive disease have

progressive disease
kidney function test
lung carcinoma
squamous non-small cell lung cancer
non-squamous non-small cell lung cancer
  • 20 views
  • 24 Nov, 2021
  • 377 locations