Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 447 clinical trials
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Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003)

Solid Tumors (RECIST) 1.1 by blinded independent central review (BICR), and with respect to overall survival (OS), in participants with non-small cell lung cancer.

ROS1
EGFR
lung cancer
epidermal growth factor
growth factor
  • 1 views
  • 05 Dec, 2021
  • 56 locations
None
Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with olaparib placebo (Arm 1) or with olaparib (Arm 2) compared to concurrent chemoradiation therapy followed by durvalumab (Arm 3) in participants with unresectable, locally advanced …

durvalumab
lung cancer
etoposide
metastasis
measurable disease
  • 51 views
  • 05 Dec, 2021
  • 198 locations
None
A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)

The main objective of the study is to evaluate dose-exposure and safety of nintedanib in children and adolescents with fibrosing Interstitial Lung Disease (ILD).

fibrosis
pulmonary disease
nintedanib
  • 7 views
  • 05 Dec, 2021
  • 84 locations
None
Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

combination with zimberelimab and etrumadenant (AB928) in front-line, PD-L1 positive, metastatic non-small cell lung cancer.

EGFR
lung cancer
epidermal growth factor
growth factor
cancer
  • 62 views
  • 27 Nov, 2021
  • 147 locations
None
Study to Evaluate Monotherapy Compared to Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer.

EGFR
lung cancer
epidermal growth factor
growth factor
pemetrexed
  • 40 views
  • 27 Nov, 2021
  • 186 locations
None
A Study to Evaluate the Safety Pharmacokinetics and Pharmacodynamics of Ivacaftor in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age and Have an Ivacaftor-Responsive CFTR Mutation

The purpose of this study is to evaluate the safety of ivacaftor treatment, and PK of ivacaftor and metabolites in subjects with cystic fibrosis (CF) who are <24 months of age at treatment initiation and have an ivacaftor-responsive CF transmembrane conductance regulator (CFTR) gene mutation.

sweat test
ivacaftor
fibrosis
  • 0 views
  • 05 Dec, 2021
  • 23 locations
None
A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222

This study will evaluate the safety, tolerability, and efficacy of ABBV-3067 given alone and in combination with various doses of ABBV-2222 in adults with Cystic Fibrosis who are homozygous for the F508del mutation.

pulmonary function test
fibrosis
  • 122 views
  • 02 Dec, 2021
  • 115 locations
None
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

albuterol
copd exacerbation
muscarinic antagonists
cigarette smoke
fluticasone
  • 400 views
  • 05 Dec, 2021
  • 238 locations
None
Tezepelumab COPD Exacerbation Study

Obstructive Pulmonary Disease (COPD)

bronchodilator
ct scan
copd exacerbation
severe chronic obstructive pulmonary disease
  • 131 views
  • 30 Nov, 2021
  • 112 locations
None
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

corticosteroids
severe chronic obstructive pulmonary disease
eosinophil count
antibiotics
bronchodilator
  • 854 views
  • 05 Dec, 2021
  • 472 locations