Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 277 clinical trials
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer (NeoCOAST-2)

resectable, early-stage non-small cell lung cancer

lung carcinoma
durvalumab
epidermal growth factor
EGFR
epidermal growth factor receptor
  • 0 views
  • 09 Aug, 2022
  • 13 locations
AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)

The main purpose of this study is to evaluate the safety, tolerability, and recommended phase 2 target dose of tarlatamab in combination with AMG 404.

brain metastases
  • 0 views
  • 11 Aug, 2022
  • 14 locations
Study of Lorlatinib In People With ALK-positive Non-small Cell Lung Cancer

The purpose of this clinical trial is to learn whether the study medicine (called lorlatinib) is safe and effective for the treatment of non-small cell lung cancer that is caused by an abnormal

metastatic non-small cell lung cancer
cancer
kinase inhibitor
lymphoma
lorlatinib
  • 4 views
  • 10 Aug, 2022
  • 23 locations
Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation (DATACOL)

Transplant results vary considerably from one organ to another. Lung transplantation has poorer long-term outcomes than other solid organ transplants, with a current median post-transplant

  • 0 views
  • 10 Aug, 2022
  • 1 location
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) (AcceleRET-Lung)

This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcomes when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for …

metastatic non-small cell lung cancer
paclitaxel
immunostimulants
carboplatin
x-rays
  • 54 views
  • 11 Aug, 2022
  • 92 locations
Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex (ARISE)

The primary objective of this study is to generate evidence demonstrating the domain specification (via modern psychometric methods), reliability, validity, and responsiveness (within-subject meaningful change) of the Patient-Reported Outcome (PRO) endpoints.

  • 35 views
  • 10 Aug, 2022
  • 131 locations
De-escalation Immunotherapy mAintenance Duration Trial for Stage IV Lung Cancer Patients With Disease Control After Chemo-immunotherapy Induction (DIAL)

Immunotherapeutic approaches recently have demonstrated clinical efficacy in several cancer types, including melanoma and NSCLC. As a matter of fact, first registration trials of immune-checkpoints inhibitors (ICI) in second-line settings (pembrolizumab as well as nivolumab or atezolizumab) had stated that ICI could be continued until disease progression or not tolerable …

  • 0 views
  • 11 Aug, 2022
  • 2 locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. Immunotherapy with

cardiotoxic agents
leptomeningeal disease
measurable disease
tyrosine
pembrolizumab
  • 322 views
  • 09 Aug, 2022
  • 771 locations
The Effect of Dupilumab on Lung Function and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma (VESTIGE)

Primary Objective: To assess the effect of dupilumab on lung function and related changes in airway volumes detectable by functional respiratory imaging Secondary

fractional exhaled nitric oxide
bronchodilator
leukotriene receptor antagonist
spirometry
pulmonary function test
  • 24 views
  • 09 Aug, 2022
  • 69 locations
A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer (NeoADAURA)

treatment of patients with resectable EGFRm Non-Small Cell Lung Cancer

lung carcinoma
osimertinib
EGFR
pemetrexed
carboplatin
  • 0 views
  • 10 Aug, 2022
  • 125 locations