Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 719 clinical trials
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism

There are many available treatments for pulmonary embolism (PE), but the best treatment for this condition is not known. The HI-PEITHO study will compare two treatment options that are both available on the market for the treatment of PE. Patients will be randomized 1:1 to receive either blood thinners (anticoagulation) …

blood clot
pulmonary angiography
angiography
troponin
clot
  • 0 views
  • 19 Jan, 2022
  • 36 locations
Protective Ventilation With High Versus Low PEEP During One-lung Ventilation for Thoracic Surgery

One-lung ventilation (OLV) with resting of the contralateral lung may be required to allow or facilitate thoracic surgery. However, OLV can result in severe hypoxemia, requiring a mechanical

  • 1 views
  • 17 Jan, 2022
  • 34 locations
Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer

Some patients with limited disease small-cell lung cancer (LD SCLC) are cured after chemo-radiotherapy, but the majority relapse and die from their cancer. Better therapy is needed

atezolizumab
neutrophil count
cancer chemotherapy
  • 60 views
  • 09 Jan, 2022
  • 66 locations
Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)

-resistant small-cell lung cancer (SCLC). This study will be conducted in two parts: safety run-in part and main part. The safety run-in part will be conducted in Japan.

topotecan
measurable disease
carboplatin
  • 0 views
  • 21 Jan, 2022
  • 52 locations
Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer: RCT

incisions, and the lung resection is completed. Robotic thoracic surgery (RTS) uses a similar minimally invasive approach, but the very precise instruments involved with RTS allow the surgeon to view the

pulmonary resection
lung carcinoma
lung cancer
lung lobectomy
thoracotomy
  • 66 views
  • 29 Jan, 2022
  • 1 location
Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin (GRAY-ZONE)

The study evaluates the effect of platelet inhibition and / or lipid lowering in non-ACS-patients with symptoms suggestive for ACS, and elevated high-sensitivity troponin values

  • 6 views
  • 26 Jan, 2022
  • 6 locations
Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

This study is to help determine the most effective type or combination of treatments to offer patients seeking lung cancer screening who are smokers to help them reduce the number of cigarettes

tobacco smoke
Accepts healthy volunteers
cigarette smoke
nicotine replacement
cancer
  • 892 views
  • 26 Dec, 2021
  • 19 locations
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that

monoclonal antibody therapy
lung cancer
measurable disease
tumor cells
paclitaxel
  • 141 views
  • 19 Jan, 2022
  • 593 locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. Immunotherapy with

lung cancer
oophorectomy
measurable disease
thyroxine
international normalized ratio
  • 314 views
  • 20 Jan, 2022
  • 837 locations
Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE. This study is designed to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of edoxaban and to compare the efficacy and safety of edoxaban against standard of care in …

probe
thromboembolism
venous thromboembolism
vitamin k
heparin therapy
  • 0 views
  • 26 Jan, 2022
  • 117 locations