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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (3201) clinical trials

Determine the safety, tolerability and maximum tolerated dose of anetumab ravtansine (BAY 94-9343) in combination with pemetrexed 500 mg/m2 and cisplatin 75 mg/m2 in subjects with mesothelin-expressing predominantly epithelial mesothelioma or nonsquamous non-small-cell lung cancer.

Phase

To characterize the safety, tolerability, pharmacokinetics and immunogenicity of anetumab ravtansine in subjects with advanced solid cancers and with different degrees of hepatic or renal impairment

Phase

Characterize the safety, tolerability, ECG effects, pharmacokinetics and immunogenicity of anetumab ravtansine given as single agent and after inhibition of CYP3A4 and P-gp by concomitant administration of itraconazole in subjects with mesothelin-expressing advanced solid cancers

Phase

The relatively restricted C4.4a expression pattern provides a target for the selective delivery of a cytotoxic drug to C4.4.a-expressing tumor cells by means of a suitable antibody-drug conjugate. The subject population eligible for the current study will be those subjects with advanced malignancies known to express C4.4a, which are refractory ...

Phase

- This is the first study where BAY1163877 is given to humans. Impact of the study is to evaluate if patients with advanced solid cancers show advanced clinical benefit under the treatment with the pan FGFR inhibitor. Patients (all comers) will receive the study drug treatment in a dose-escalation scheme ...

Phase

The objective of the trial is to investigate the efficacy and safety of 150 mg bid nintedanib in patients with PF-ILD compared to placebo over 52 weeks (Part A). The primary objective is to demonstrate a reduction in lung function decline, as measured by the annual rate of decline in ...

Phase

We are looking for individuals to participate in a research study to determine the safety and efficacy of an investigational medication. Eligibility Criteria: If you are: - 40 years of age or older - are a previous or current smoker - have a diagnosis of chronic obstructive pulmonary disease (COPD) ...

Phase N/A

Researchers at the University of Kentucky are conducting a study to investigate the safety and how well the inhaled investigational drug treprostinil works in people with pulmonary hypertension associated with lung disease. This study will look at your ability to exercise after taking the study drug. You may be eligible ...

Phase N/A

A research study is evaluating an investigational oral medication for non-small cell lung cancer (NSCLC). This research study may be an option if you: • Are at least 18 years of age • Have been diagnosed with stage IIIB or IV metastatic NSCLC • Have fully recovered from any previous ...

Phase N/A

People with heart failure are asked to participate in a research study being conducted by Montefiore Medical Center. The MANAGE-HF study intends to evaluate whether proper clinical integration of HeartLogic, a remote monitoring diagnostic feature in Boston Scientific ICDs and CRT-Ds, can reduce heart failure hospitalization or other heart failure ...

Phase N/A