Pediatric Health Clinical Trials

A listing of Pediatric Health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 99 clinical trials
Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer With and Without Intra-operative RT: a Window of Opportunity Study (Pembro/IORT)

Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatment naive triple negative breast cancer (TNBC) patients. Assess for change in tumor-infiltrating lymphocytes (TILS) both stromal (sTILS) and intraepithelial (iTILS) in newly diagnosed early stage TNBC patients treated with two doses of …

erbb2
progesterone
triple negative breast cancer
mk-3475
breast carcinoma
  • 40 views
  • 28 Oct, 2022
  • 1 location
Explosive Synchronization of Brain Network Activity in Chronic Pain

This project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM). The study design has three components, however, only 2 aims are enrolling participants. The first part (Aim1) is a cross sectional assessment of brain network explosive synchronization …

functional magnetic resonance imaging
chronic pain
Accepts healthy volunteers
  • 15 views
  • 15 Oct, 2022
  • 1 location
Energy Expenditure Responses to Different Temperatures

Background The way that the body burns calories is known as energy expenditure. Some studies show that when we are cold, we burn more calories to keep our bodies warm. Brown fat is a special kind of fat that can use energy to keep the body warm. Small animals and …

fats
Accepts healthy volunteers
  • 83 views
  • 23 Oct, 2022
  • 1 location
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance

This study utilizes infusions of kisspeptin in healthy women to isolate the impact of kisspeptin on beta-cell responsivity assessed by the mixed meal tolerance test.

diabetes
Accepts healthy volunteers
chronic disease
body mass index
illicit drugs
  • 0 views
  • 04 Oct, 2022
  • 1 location
Targeted Physiotherapeutic Treatment for Aromatase Inhibitor-associated Musculoskeletal Pain in Breast Cancer Survivors: a Randomized Controlled Trial (AIMSS)

The primary objective of this trial is to assess the efficacy of targeted individualised physiotherapeutic treatment on aromatase inhibitor-associated musculoskeletal pain. This trial asks a critical, previously unaddressed, question of clinical importance about management of musculoskeletal (MSK) pain secondary to aromatase inhibitor (AI) treatment of hormone receptor-positive breast cancer. Many …

cancer
pain relieving
acupuncture
  • 1 views
  • 28 Oct, 2022
  • 1 location
Pilot Study of Mobile Attention Training in Overweight Female Adolescents

Background People are constantly exposed to unhealthy foods. Some studies of adults show that training attention away from unhealthy foods might reduce overeating. Researchers want to see what happens in the brain when teens train their attention away from food through a program on a smartphone. Objective To study the …

dxa scan
x-rays
Accepts healthy volunteers
eating disorder
body mass index
  • 246 views
  • 19 Oct, 2022
  • 1 location
The Effect of Pretreatment With Roc on Succinylcholine Myalgias

Succinylcholine is a medication (depolarizing muscle relaxant) that is used as part of an anesthetic (going to sleep for surgery). This medication can cause significant muscle soreness. Rocuronium is a medication (non-depolarizing muscle relaxant) that some anesthesia providers believe may reduce muscle soreness caused by succinylcholine if given prior, but …

soreness
  • 0 views
  • 07 Oct, 2022
  • 1 location
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists

Background Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps the body burn energy. Objective To learn more about how BAT works to burn energy. Eligibility Healthy people …

insulin resistance
vitamins
insulin sensitivity
hysterectomy
body mass index
  • 340 views
  • 24 Oct, 2022
  • 1 location
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder

Background Problem drinking affects nearly half the people who drink alcohol. Drinking alcohol affects a person s social behavior and brain structure, but researchers don t have a good understanding of how. They want to test a technique called neurofeedback to learn more about how to treat problem drinking. Objectives …

alcohol test
alcohol use disorder
alcohol abuse
tests mental
scid
  • 42 views
  • 07 Oct, 2022
  • 1 location
The Role of Proprioceptive Deficits and Psychosocial Factors in Pregnancy-related Pelvic Girdle Pain: a Follow-up Study

A large proportion of pregnant women develop pregnancy-related low back and/or pelvic girdle pain (PPGP), which often does not recover spontaneously postpartum. As a result, 10% of women with PPGP still reports complaints a decade after delivery. The prevention and treatment of PPGP are thus crucial. However, the underlying mechanisms …

depression
anxiety
  • 0 views
  • 04 Oct, 2022
  • 1 location