Pediatric Health Clinical Trials

A listing of Pediatric Health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 67 clinical trials
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Phase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer (TNBC)

triple-negative breast cancer
breast cancer
measurable disease
cancer
mammogram
  • 1387 views
  • 30 Jul, 2021
  • 310 locations
A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer

Study MO39874 is an open-label, phase IIIb, single arm, multicenter study conducted in participants with unresectable locally advanced or metastatic PD-L1-positive Triple-Negative Breast Cancer (TNBC) who have not received chemotherapy for their unresectable locally advanced or metastatic disease.

breast adenocarcinoma
programmed cell death 1 ligand 1
serum pregnancy test
measurable disease
adenocarcinoma of the breast
  • 146 views
  • 01 Aug, 2021
  • 163 locations
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adults Adolescents and Children in India and Healthy Adolescents and Children in the Republic of South Africa

The primary objective of this study is to demonstrate the non-inferiority of immunogenicity of a single dose of MenACYW conjugate vaccine compared to Menactra in adolescents and children aged 2 to 17 years in terms of serum bactericidal assay using human complement (hSBA) titers. The secondary objectives of the study …

  • 86 views
  • 26 Jul, 2021
  • 12 locations
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

Background People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective To study if social and …

pain assessment
heat
  • 61 views
  • 02 Aug, 2021
  • 1 location
Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)

The purpose of this study is to compare the efficacy of olaparib (MK-7339) plus pembrolizumab (MK-3475) with chemotherapy plus pembrolizumab after induction with first-line chemotherapy plus pembrolizumab in triple negative breast cancer (TNBC). The primary hypotheses are: Olaparib plus pembrolizumab prolongs progression-free survival (PFS) compared with chemotherapy plus pembrolizumab. Olaparib …

pembrolizumab
measurable disease
triple negative breast cancer
breast cancer
taxane
  • 241 views
  • 02 Aug, 2021
  • 134 locations
A Research Study Investigating Mim8 in People With Haemophilia A

This study consists of 2 parts. Part 1 looks at the safety and tolerability when the study medicine Mim8 is given to healthy subjects for the first time. The obtained results will help to perform a second part of the study with patients who suffer from a bleeding disorder called …

blood test
electrocardiogram
  • 190 views
  • 21 Jul, 2021
  • 28 locations
Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

This is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in adult patients with advanced or metastatic TNBC. During the dose-escalation part of each treatment arm, patients will be treated with fixed doses …

estrogen
erbb2
progesterone
estrogen receptor
measurable disease
  • 44 views
  • 02 Aug, 2021
  • 13 locations
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

This study is designed to determine the efficacy and safety of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple negative breast cancer

triple negative breast cancer
breast cancer
antineoplastic
trastuzumab
HER2
  • 400 views
  • 02 Aug, 2021
  • 65 locations
Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses

Background Researchers think that people s mental health and behavior will be very affected by the steps taken to slow the spread of COVID-19, such as social distancing. Also, the threat of disease and death, to people and their loved ones, can cause much stress. Researchers want to learn more …

anxiety
covid-19
  • 327 views
  • 01 Aug, 2021
  • 1 location
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

heart disease
angiography
diabetes
metabolic syndrome
cardiovascular disease
  • 105 views
  • 01 Aug, 2021
  • 1 location